IL-1 alpha ELISA Kits

ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for IL-1 alpha are available for Human, Mouse, Rat, Bovine and Equine which can be quantified in various samples, including serum, supernatant, plasma, urine.

Invitrogen... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for IL-1 alpha are available for Human, Mouse, Rat, Bovine and Equine which can be quantified in various samples, including serum, supernatant, plasma, urine.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated.... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for IL-1 alpha are available for Human, Mouse, Rat, Bovine and Equine which can be quantified in various samples, including serum, supernatant, plasma, urine.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for IL-1 alpha are available for Human, Mouse, Rat, Bovine and Equine which can be quantified in various samples, including serum, supernatant, plasma, urine.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits are ready-to-use and quality tested for sensitivity, specificity, precision and lot-to-lot consistency.

IL-1 alpha detection is also available using highly-sensitive ProQuantum Immunoassays. These assays provide a fast, easy workflow with no wash steps, and are detectable with any real-time PCR instrument.

Can't find what you’re looking for? Try the ELISA Builder to design your own assay based on target type and experimental needs. We also offer custom ELISA development services.

Target Information

IL-1 alpha (Interleukin-1 alpha) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 alpha is coded by the IL1A gene and signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 beta. IL1A is located on the q arm on chromosome 2 at position 13. IL-1 alpha plays an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses. IL-1 alpha activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition. IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. Further, IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury and induces apoptosis. The IL1A gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. IL1 alpha regulates the activities of NF-kappaB and mitogen-activated protein kinases. IL-1 alpha can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-1 alpha are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Synonyms

CTLA8; hematopoietin-1; IL 1 a; IL 1α; IL1; IL-1 alpha; IL17; IL1A; Il-1a; IL-1alpha; IL1-ALPHA; IL1F1; IL1α; ILN; Interleukin; interleukin 1 alpha; interleukin 1, alpha; interleukin 17; interleukin 1a; interleukin 1-alpha; interleukin 1-alpha (AA 1 - 152); Interleukin1 alpha; interleukin-1 alpha; interleukin-1 alpha precursor; Interleukin-17A; preinterleukin 1 alpha; pre-interleukin-1 alpha; pro-interleukin-1-alpha; RP23-160G19.8

IL-1 alpha ELISA Kits

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