Thermo Scientific Pierce EMCS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of aRead more
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Catalog number 22308
Price (USD)/ 50 mg
492.00
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Price (USD)/ 50 mg
492.00
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EMCS (N-ε-malemidocaproyl-oxysuccinimide ester)
Catalog number22308
Price (USD)/ 50 mg
492.00
-
Add to cart
Thermo Scientific Pierce EMCS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length spacer arm (9.4 angstroms).
Features of EMCS:
• Reactive groups: NHS ester and maleimide • Reactive towards: amino and sulfhydryl groups • C6-homolog of aliphatic spacer series which includes AMAS, BMPS, GMBS and EMCS • NHS ester end couples with primary amines at pH 7-9 to form stable amide bonds • Maleimides react with -SH groups at pH 6.5-7.5, forming stable thioether linkages • Non-cleavable • Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-EMCS • Increased sphere of coupling vs. GMBS • Short aliphatic spacer has low potential for eliciting an immune response
Product References: Crosslinker Application Guide -- search for recent literature references for this product
For Research Use Only. Not for use in diagnostic procedures.