Thermo Scientific™
AMAS (N-α-maleimidoacet-oxysuccinimide ester)
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Description
Thermo Scientific Pierce AMAS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a very short spacer arm (4.4 angstroms).Features of AMAS:
• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Shortest of aliphatic spacer series which includes AMAS, BMPS, GMBS and EMCS
• NHS ester end couples with primary amines at pH 7-9, forming stable amide bonds
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming stable thioether linkages
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
• Very short aliphatic spacer has low potential for eliciting an immune response
For Research Use Only. Not for use in diagnostic procedures.
Specifications
| Crosslinker Type: | Heterobifunctional |
|---|---|
| Labeling Method: | Chemical Labeling |
| Product Line: | Pierce™ |
| Product Size: | 50 mg |
| Solubility: | DMF (Dimethylformamide), DMSO (Dimethylsulfoxide) |
| Spacer: | Short |
Contents & storage
Store desiccated at 4°C.
