BMPS (N-β-maleimidopropyl-oxysuccinimide ester)

Catalog number: 22298

Thermo Scientific™  Related applications: Protein Labeling & Crosslinking

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Description

Thermo Scientific Pierce BMPS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (5.9 Å).

Features of BMPS:

Reactive groups: NHS ester and maleimide
Reactive towards: amino and sulfhydryl groups
• C3-homolog of aliphatic spacer series which includes AMAS, BMPS, GMBS and EMCS
• NHS ester end couples with primary amines at pH 7-9, forming stable amide bonds
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming stable thioether linkages
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
• Short aliphatic spacer has low potential for eliciting an immune response

Product References:

Crosslinker Application Guide -- search for recent literature references for this product
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Spacer: Short
Solubility: DMF (Dimethylformamide), DMSO (Dimethylsulfoxide)
Product Size: 50 mg
Labeling Method: Chemical Labeling
Crosslinker Type: Heterobifunctional

Contents & storage

Store desiccated at 4°C. Shipped at ambient temperature.

Documents

Manuals & protocols