Thermo Scientific™

Pierce™ Hydroxylamine-HCl

Catalog number:  26103

 Related applications:

Protein Labeling & Crosslinking

Error loading your content!

  Catalog number
Select a plan
Unit size
Price ({{currency}}) Availability Qty
{{product.sku}} {{product.sku}} also known as {{product.formattedSku}} 
Pro add-ons

Your on-site stock

›› {{supplyCenter.scName}}({{scProduct.stockOnHand}} In stock)
›› {{supplyCenter.scName}}(Out of stock)
›› {{supplyCenter.scName}}
This item is not currently available on-site. Depending on your Supply Center settings you may be able to add the item to cart above else use the Order Non-Stocked Items' tab on the Supply Center home page.
Back to top


Thermo Scientific Pierce Hydroxylamine-HCl has many uses, which include cleaving Asn-Gly peptide bonds and deprotecting (exposing) sulfhydryls on SATA-modified molecules for conjugation.

Features of Hydroxylamine-HCl:

• Quench amine-labeling or crosslinking reactions (e.g., with NHS esters)
• Expose protected sulfhydryl groups on SATA-modified molecules
• Cleave carbonyl-containing crosslinkers such as EGS and Sulfo-EGS

Hydroxylamine·HCl is a strong reducing agent that is useful in biochemical crosslinking applications, including the deacetylation of SATA and chemical cleavage of EGS and Sulfo-EGS. Hydroxylamine converts carbonyl compounds (aldehydes and ketones) to their oxime derivatives in the presence of a weak base. Therefore, crosslinkers and other compounds that contain a carbonyl within their structure are cleavable with hydroxylamine·HCl.
For Research Use Only. Not for use in diagnostic procedures.


Product Line: Pierce™
Product Size: 25 g

Contents & storage

Upon receipt store desiccated at room temperature. Product shipped at ambient temperature.


Manuals & protocols