Produce cryo-lamellas for cryo-tomography using autoloader TEM systems.Cryo-dedicated hardware inside the DualBeam system chamber ensures optimal sample preparation while maintaining cryo conditions. Cryo specimens are mounted in dedicated Cryo-FIB AutoGrids which can be loaded into AutoLoader TEM systems.
Create thinner cryo-lamella without cutting artifacts. Ion beam milling enables creation of compression-free cryo-lamella samples for TEM tomography imaging. This method avoids artifacts such as mechanical compression inevitable for mechanical cryo-sectioning approaches using cryo-ultramicrotomes.
Improve sample preparation precision. Guided user software and Thermo Scientific™ MAPS™ correlation software makes the Aquilos Cryo-FIB easy to use, even for inexperienced users.Enhanced sample integrity
The ability to properly prepare thin lamellas from vitrified samples, while at the same time, maintaining the necessary temperature, vacuum and transfer conditions, has been a significant challenge for researchers. To remove that impediment and make tomography accessible to a much broader community of researchers and scientists, the Aquilos Cryo-FIB features an integrated, fully rotatable cryo-stage and adjacent cryo-hardware that protects the frozen-hydrated samples from contamination, ensuring that delicate life science cryo-samples will be kept at vitreous temperatures ( < -165°C) at all times.
Integrated into cryo-tomography workflow
The Aquilos Cryo-FIB is specifically designed to complete our cryo-tomography workflow: