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          System Message

          OKCancel
          LOADING ...
          Gene:
          TP63
          Transcript:
          NM_001114979.1
          Assay Name:
          Mutation genome location:
          chr.3 189866593-189866866 on build GRCh38
          Assay ID Hs00603947_CE

          Purification
          Size
          Availability Made To Order
          Catalog # A15629
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • Assay Details
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          Genomic Map

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          Assay Details


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          More Information


          Set Membership:

          Between 200-400 bp

          Panther Classification:

          Molecular Function -

          P53-like transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          replicative cell aging
          skeletal system development
          establishment of planar polarity
          positive regulation of mesenchymal cell proliferation
          epithelial cell development
          chromatin remodeling
          transcription from RNA polymerase II promoter
          apoptotic process
          DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
          Notch signaling pathway
          spermatogenesis
          ectoderm and mesoderm interaction
          proximal/distal pattern formation
          response to X-ray
          multicellular organism aging
          response to gamma radiation
          epidermal cell division
          regulation of epidermal cell division
          positive regulation of keratinocyte proliferation
          keratinocyte differentiation
          embryonic limb morphogenesis
          polarized epithelial cell differentiation
          hair follicle morphogenesis
          mitotic G1 DNA damage checkpoint
          cellular response to UV
          post-anal tail morphogenesis
          odontogenesis of dentin-containing tooth
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          regulation of apoptotic process
          negative regulation of apoptotic process
          regulation of cysteine-type endopeptidase activity involved in apoptotic process
          regulation of neuron apoptotic process
          skin morphogenesis
          keratinocyte proliferation
          negative regulation of keratinocyte differentiation
          positive regulation of osteoblast differentiation
          positive regulation of Notch signaling pathway
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          sympathetic nervous system development
          smooth muscle tissue development
          female genitalia morphogenesis
          protein homotetramerization
          neuron apoptotic process
          urinary bladder development
          cloacal septation
          prostatic bud formation
          squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
          establishment of skin barrier
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of signal transduction by p53 class mediator
          positive regulation of fibroblast apoptotic process
          negative regulation of mesoderm development
          transcription factor activity, transcription factor binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          p53 binding
          DNA binding
          chromatin binding
          damaged DNA binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          identical protein binding
          sequence-specific DNA binding
          transcription regulatory region DNA binding
          metal ion binding
          WW domain binding

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          Host server : magellan-search-green-b49b87d85-5cvsx:80/100.66.79.163:80.
          git-commit: 5b8c860b7cdb41e9cfe07630520f6b51e109d38e
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.47.0-Offline