Slide-A-Lyzer Discontinuation | Thermo Fisher Scientific

As part of our commitment to innovation and excellence, we are discontinuing a part of our current Slide-A-Lyzer product line to make way for the advanced G3 Slide-A-Lyzer cassettes that offer remarkable benefits for your laboratory needs.

Self-flotation—no external flotation devices or clips needed
Redesigned cap—secure locking cap with a wide opening for easy sample access
Green certified—uses 23–68% less plastic, helping support sustainability
Multiple sizes and MWCOs—available in 2K, 3.5K, 10K, and 20K MWCOs for 1–25 mL samples
Sterile option—E-beam-irradiated 10K MWCO cassettes available
Compact design—saves valuable lab space

Tentative effective date: December 31, 2025

Upgrade to Slide-A-Lyzer G3 Dialysis Cassettes and elevate your research. If you're interested in a sample of the new Slide-A-Lyzer G3 dialysis cassettes, please contact your local sales representative.

See Slide-A-Lyzer products

Read fact sheet

Please see the table below for a list of affected products and their substitutes.

Affected products and their substitutes

Slide-A-Lyzer Dialysis Cassettes MWCO 2K

Discontinued product	Volume	Replacement product	Volume	Quantity	Catalog #
66205	0.5 mL	Slide-A-Lyzer MINI Dialysis Devices	0.1 mL	50 devices*	69580
66203	3 mL	Slide-A-Lyzer G3 Dialysis Cassettes	3 mL	10 cassettes	A52961
66212	12 mL	Slide-A-Lyzer G3 Dialysis Cassettes	15 mL	8 cassettes	A52962
66230	30 mL	Slide-A-Lyzer G3 Dialysis Cassettes	30 mL	6 cassettes	A52963
New size		Slide-A-Lyzer G3 Dialysis Cassettes	125 mL	6 cassettes	A52965

*Not an equivalent alternative. The Slide-A-Lyzer MINI Dialysis Device 10K MWCO, 0.1 mL (Cat # 69580) are suitable for 10–100 µL samples, while the Slide-A-Lyzer G1 Dialysis Cassettes 2K MWCO, 0.5 mL (Cat # 66205) accommodates 100–500 µL sample volumes.

Slide-A-Lyzer Dialysis Cassettes MWCO 3.5K

Discontinued product	Volume	Replacement product	Volume	Quantity	Catalog #
66333	0.5 mL	Slide-A-Lyzer MINI Dialysis Devices	0.5 mL	25 devices	88400
66330	3 mL	Slide-A-Lyzer G3 Dialysis Cassettes	3 mL	10 cassettes	A52966
66110	12 mL	Slide-A-Lyzer G3 Dialysis Cassettes	15 mL	8 cassettes	A52967
66130	30 mL	Slide-A-Lyzer G3 Dialysis Cassettes	30 mL	6 cassettes	A52968
New size		Slide-A-Lyzer G3 Dialysis Cassettes	125 mL	6 cassettes	A52970

Slide-A-Lyzer Dialysis Cassettes MWCO 7K

Discontinued product	Volume	No equivalent alternative available. Use the 3.5K MWCO G3 Slide-A-Lyzer and/or MINI Dialysis Devices replacement products listed above.
66373	0.5 mL
66370	3 mL
66710	12 mL

Slide-A-Lyzer Dialysis Cassettes MWCO 10K

Discontinued product	Volume	Replacement product	Volume	Quantity	Catalog #
66383	0.5 mL	Slide-A-Lyzer MINI Dialysis Devices	0.5 mL	25 devices	88401
66380	3 mL	Slide-A-Lyzer G3 Dialysis Cassettes	3 mL	10 cassettes	A52971
66810	12 mL	Slide-A-Lyzer G3 Dialysis Cassettes	15 mL	8 cassettes	A52972
66830	30 mL	Slide-A-Lyzer G3 Dialysis Cassettes	30 mL	6 cassettes	A52973
New size		Slide-A-Lyzer G3 Dialysis Cassettes	125 mL	6 cassettes	A52975
66454	0.5 mL	No equivalent alternative available.
66455	3 mL	Slide-A-Lyzer G3 Dialysis Cassettes E-Beam Irradiated	3 mL	10 cassettes	A52981
66453	12 mL	Slide-A-Lyzer G3 Dialysis Cassettes E-Beam Irradiated	15 mL	8 cassettes	A52982
66456	30 mL	Slide-A-Lyzer G3 Dialysis Cassettes E-Beam Irradiated	30 mL	6 cassettes	A52983
New size		Slide-A-Lyzer G3 Dialysis Cassettes E-Beam Irradiated	125 mL	6 cassettes	A52985

Slide-A-Lyzer Dialysis Cassettes MWCO 20K

Discontinued product	Volume	Replacement product	Volume	Quantity	Catalog #
66005	0.5 mL	Slide-A-Lyzer MINI Dialysis Devices	0.5 mL	25 devices	88402
66003	3 mL	Slide-A-Lyzer G3 Dialysis Cassettes	3 mL	10 cassettes	A52976
66012	12 mL	Slide-A-Lyzer G3 Dialysis Cassettes	15 mL	8 cassettes	A52977
66030	30 mL	Slide-A-Lyzer G3 Dialysis Cassettes	30 mL	6 cassettes	A52978
New size		Slide-A-Lyzer G3 Dialysis Cassettes	125 mL	6 cassettes	A52980

Contact us

If you have any questions regarding the transition or if we can be of assistance in any way, please feel free to contact our customer service.

For Research Use Only. Not for use in diagnostic procedures.

Original Slide-A-Lyzer Dialysis Cassettes Discontinuation