Use the lists below to identify the genes and pathways for which Life Technologies offers high-throughput screening assays.

Genes

ABL1 - CSNK CXCR - GSK H1 - MERTK MET - PRAS40 PRK - ZAP

5HT1A
ABL1
ABL1 E255K
ABL1 G250E
ABL1 T315I
ABL1 Y253F
ABL2
ACVR1
ACVR1B
ACVR2A
ACVR2B
ADCYAP1R1
ADORA1
ADORA2A
ADORA2B
ADORA3
ADRA1A
ADRA1B
ADRA2A
ADRB1
ADRB2
ADRB3
ADRBK1
ADRBK2
AGTR1
AGTRL1
AKT1
AKT2
AKT3
ALK5
ALK7
AMPK
AMPK (A1/B1/G1)
AMPK (A2/B1/G1)
AR
ATF2
ATF6
AURKA
AURKB
AVPR1A
AVPR2
AXL
BDKRB1
BDKRB2
Beta-Catenin
BKR1
BLK
BLK1
BMPR1A
BMX
BRAF
BRAF V599E
BRAF V600E
BRSK1
BTK
c/EBPa
C/EBPa
C5AR1
CALCR2
CALCRL:RAMP1
CALCRL:RAMP2
CALCRL:RAMP3
CAMK1
CAMK1D
CAMK2A
CAMK2B
CAMK2D
CAMK4
CAMKK1
CAMKK2
cAMP
CAR
CASR
CCKAR
CCKBR
CCR1
CCR2
CCR3
CCR4
CCR5
CCR6
CCR7
CDC42BPA
CDC42BPB
CDK1
CDK2
CDK5
CDK7
CDK7/cyclin H/MNAT1
CDK8
CDK9/Cyclin K
CDK9/Cyclin T1
CHEK1
CHEK2
CHRM2
CHRM5
CHUK
c-Jun
CLK1
CLK2
CLK3
CLK4
c-MET
CMKLR1
CNR1
CNR2
CRHR1
CRHR2
CRTH2
CSF1R
CSK
CSNK1A1
CSNK1D
CSNK1E
CSNK1G1
CSNK1G2
CSNK1G3
CSNK2A1
CSNK2A2

CXCR1
CXCR2
CXCR3
CXCR4
CXCR6
CXCR7
CysLT2
D1
D2
D5
DAPK1
DAPK2
DAPK3
DCAMKL2
DDR1
DDR2
DMPK
DNAPK
DRD1
DRD2
DRD5
DYRK1A
DYRK1B
DYRK3
DYRK4
EDG1
EDG2
EDG3
EDG4
EDG6
EDG7
EDG8
EDNRA
EDNRB
EEF2K
EGFR
EGFR L858R
EGFR L861Q
EGFR T790M
EGFR T790M L858R
EIF2AK1
EIF2AK2
EIF2AK3
EPHA
EPHA1
EPHA2
EPHA3
EPHA4
EPHA5
EPHA7
EPHA8
EPHB1
EPHB2
EPHB3
EPHB4
ER alpha
ER beta
ERA
ERB
ERBB2
ERBB4
ERK1/2
ERK2
ERR alpha
ERR1
ERR2
ERR3
ESR1
ESR2
ESRRA
ESRRB
ESRRG
F2RL1
FER
FES
FGFR1
FGFR2
FGFR3
FGFR3 K650E
FGFR4
FGR
FLT1
FLT3
FLT3 D835Y
FLT4
FOXO3
FPRL-1
FRAP1
FRAP1 (mTOR)
FRK
FXR
FYN
G2A
GALR1
GALR2
GCGR
GHSR
GIPR
GLP1R
GLP2R
GnRHR
GPR1
GPR10
GPR109A
GPR119
GPR120S
GPR132
GPR145
GPR21
GPR23
GPR24
GPR35
GPR39
GPR44
GPR54
GPR8
GPR92
GR
GRK4
GRK5
GRK6
GRK7
GRPR
GSG2
GSK3A
GSK3B
H1
H2
H3
H4
HCK
HCRTR1
HCRTR2
hERG
HIF1 alpha
HIPK1
HIPK3
HIPK4
Histone H3
HRH1
HRH2
HRH3
HRH4
HSF-1
HTR1A
HTR1D
HTR2A
HTR2B
HTR2C
HTR7
I kappa B
IFG1R
IGF1R
IGF-1R
IGFR1
IkB alpha
IKBKB
IKBKE
IKK
INSR
INSRR
IR
IRAK
IRAK1
IRAK4
IRF3
ITK
JAK1
JAK2
JAK2 (V617F)
JAK2 JH1 JH2
JAK2 JH1 JH2 V617F
JAK3
JNK
KDR
Kir1.1
Kir2.1
KIT
KIT T670I
KIT V654A
Kv1.1
Kv1.3
Kv2.1
Kv7.2
Kv7.3
LCK
LIMK1
LIMK2
LRRK2
LRRK2 D1994A
LRRK2 G2019S
LRRK2 I2020T
LRRK2 R1441C
LTB4R
LTK
LXR alpha
LXR beta
LXRA
LXRB
LYNA
LYNB
M1
M2
M3
M4
M5
MAP2K1
MAP2K1 S218D S222D
MAP2K2
MAP2K3
MAP2K6
MAP2K6 S207E T211E
MAP3K10
MAP3K11
MAP3K14
MAP3K2
MAP3K3
MAP3K5
MAP3K7/MAP3K7IP1
MAP3K8
MAP3K9
MAP4K2
MAP4K4
MAP4K5
MAPK1
MAPK10
MAPK11
MAPK12
MAPK13
MAPK14
MAPK3
MAPK8
MAPK9
MAPKAPK2
MAPKAPK3
MAPKAPK5
MARK1
MARK2
MARK3
MARK4
MATK
MC1R
MC2R
MC3R
MC4R
MC5R
MCHR1
MCHR2
MEK
MELK
MERTK
MET
MET M1250T
MINK1
MKNK2
MLCK
MLNR
MLYK2
MR
MST1R
MST4
MTNR1A
MTNR1B
mTOR
MUSK
MYC
MYLK
MYLK2
Nav1.2
Nav1.5
NEK1
NEK2
NEK4
NEK6
NEK7
NEK9
NICD
NIK
NLK
NMUR1
NPSR1-A
NPSR1-B
NPY1R
NPY2R
NPY5R
NR1A1
NR1A2
NR1B1
NR1B2
NR1B3
NR1C1
NR1C2
NR1C3
NR1F1
NR1F3
NR1H2
NR1H3
NR1H4
NR1I1
NR1I2
NR1I3
NR2B1
NR2B2
NR3A1
NR3A2
NR3B1
NR3B2
NR3B3
NR3C1
NR3C2
NR3C3
NR3C4
NRF2
NTRK1
NTRK2
NTRK3
NTSR1
NUAK1
OPRD1
OPRK1
OPRL1
OPRM1
OXTR
P2RY11
P2RY14
P2RY2
P2RY4
P2RY6
p38
p53
PAC1
PAK1
PAK2
PAK3
PAK4
PAK6
PAK7
PASK
PDCD4
PDGFRA
PDGFRA D842V
PDGFRA T674I
PDGFRA V561D
PDGFRB
PDK1
PGR
PHKG1
PHKG2
PI3K
PI4KA
PI4KB
PIK3C2A
PIK3C2B
PIK3C3
PIK3CA/PIK3R1
PIK3CD/PIK3R1
PIK3CG
PIM1
PIM2
PKA
PKC
PKN1
PLK1
PLK2
PLK3
PPAR alpha
PPAR delta
PPAR gamma
PPARA
PPARD
PPARG
PR
PRAS40

PRKACA
PRKCA
PRKCB1
PRKCB2
PRKCD
PRKCE
PRKCG
PRKCH
PRKCI
PRKCN
PRKCQ
PRKCZ
PRKD1
PRKD2
PRKG1
PRKG2
PRKX
PROKR2
PTAFR
PTGDR
PTGER1
PTGIR
PTK2
PTK2B
PTK6
PXR(SXR)
RAF
RAF1 (cRaf) Y340D Y341D
RAF1 (cRAF) Y340D Y341D
RAR alpha
RAR beta
RAR gamma
RARA
RARB
RARG
RET
RET V804L
RET Y791F
RIPK2
RLN3R1
ROCK1
ROCK2
RON
ROR alpha
ROR gamma
RORA
RORG
ROS1
RPS6KA1
RPS6KA2
RPS6KA3
RPS6KA4
RPS6KA5
RPS6KA6
RPS6KB1
RXR alpha
RXR beta
RXRA
RXRB
SCTR
SGK
SGK2
SGKL
SLK
SMO
SNF1LK2
SPHK1
SPHK2
SRC
SRCN1
SRMS
SRPK1
SRPK2
SSTR1
SSTR2
SSTR5
STAT1
STAT3
STAT5
STAT6
STK16
STK17A
STK22B
STK22D
STK23
STK24
STK25
STK3
STK33
STK4
SYK
T3RB
TACR1
TACR2
TACR3
TAOK2
TAOK3
TBK1
TBXA2R
TEC
TEK
TGF beta R
TGFBR1
TGFBR2
THRA
THRB
TLR
TLR3
TNF alpha
TNK2
TR alpha
TR beta
TRKA
TRKB
TRKC
TTK
TXK
TYK2
TYRO3
VDR
VPAC1
VPAC2
WNK2
WNK3
YES1
ZAP70

Signaling Pathways

A - H J - M N - Z

Anti-oxidant response pathway
C/EBP pathway
cAMP/PKA pathway
Cell cycle pRB-E2F pathway
DNA damage/p53 response pathway
ER stress response pathway
Glucocorticoid receptor pathway
Heat shock response pathway
Hedgehog pathway
Hypoxia pathway

Interleukin 1 pathway
Interleukin 4/STAT6 pathway
JAK/STAT (GM-CSF/EPO/IL-3) pathway
JAK/STAT (IFN gamma/IL-6/OSM) pathway
JAK/STAT (IL-2) pathway
JAK/STAT (IL-3) pathway
JAK/STAT (Type I IFN) pathway
JAK/STAT pathway
MAPK pathway
Myc pathway

NF-kappa B pathway
Notch pathway
PI3K/AKT/FOXO3 pathway
PKC and calcium pathway
TGF beta/BMP pathway
TLR3/TBK1/IRF3 pathway
TNF alpha pathway
Wnt/Beta-Catenin pathway