Accessible Raman imaging for all

The Thermo Scientific™ DXR™2xi Raman imaging microscope enables users across many disciplines to quickly create information-rich chemical images without Raman expertise or a deep learning curve. It features a microscopy-first design that uses image-centric operation and built in spectroscopic profiling.

  • Save time with walk-up-and-run operation regardless of user skill level. Finally, high performance chemical imaging accessible to all
  • Optimize imaging parameters in real-time on-screen to visualize your data faster
  • Maximize sample throughput with intuitive workflow for demanding applications
  • Ensure accurate measurements
    • autoalignment and calibration – no tools required
    • automatic background compensation
  • Adaptable configuration by any user within seconds
    • change the pre-aligned laser, filter and gratings without any tools; expand your ability to take on most any sample
  • Accelerate progress across your organization with the expertise already built into the instrument
    • deep knowledge isn't required to set up the instrument, collect data or analyze results
    • share the instrument with multiple departments, getting more done with a single instrument
    • automatic feature recognition and powerful component identification simplify your analysis time

Spotlight videos

From graphene to bioscience, geology to pharmaceuticals, accelerate progress across your organization with the easy-to-use, low-maintenance DXRxi Raman imaging microscope.

Advance research in multi-user labs. Learn how a group of diverse researchers finish their investigations faster with the DXR and DXRxi Raman microscopes.


Reveal the unanticipated. The DXRxi Raman imaging microscope can deliver stunning images almost instantly, without the user needing to be an expert in spectroscopy.

Raman imaging applications

Carbon nanomaterials have a niche in materials science due to their exceptional electronic, thermal, mechanical, optical and magnetic properties, creating potential applications in a wide range of fields. Raman spectroscopy is an integral part of carbon nanomaterial research because it plays a vital role in the characterization of these materials.

Application mote:   Uncovering the Secrets Governing the Chemical Vapor Deposition of Graphene with Rapid Raman Imaging
One major challenge currently facing the graphene industry is the difficulty in controlling the quality of graphene sheets when produced over large areas using industrial scale techniques. The key to solving this challenge lies in gaining a thorough understanding of the synthetic methods used to fabricate macro-sized single-layer graphene films.

Application note:   Graphene Protective Coating Capabilities Investigated by Rapid Raman Chemical Imaging
Graphene has demonstrated exceptional barrier properties, being impenetrable to even helium. Coupled with the fact that the material is also optically transparent, this behavior has attracted intense interest in the material science area towards using graphene as a barrier layer in a variety of applications. This application note presents preliminary work investigating the protective capabilities of graphene employing the use of rapid Raman imaging.


On demand webinars

Rethinking Raman: Raman Microscopy and Imaging for Shared Academic Labs Watch now
Visualizing, Characterizing, and Analyzing Pharmaceutical Constituents with Raman Imaging Watch now
Raman Imaging: A Tool for Realizing Graphene and Graphene Composite Materials Watch now
Label-free Cellular Analysis with Raman Imaging Watch now
Rethinking Raman Imaging: Advanced Materials Characterization Watch now
Characterization of Battery Materials: Test cases for the enegery storage of tomorrow Watch now

Raman spectroscopy is an established analytical technique for geological samples. It not only provides a fast and efficient way of identifying specific materials, but it also provides considerable information for:

  • Molecular structure and chemical environments
  • Identifying various minerals using ever expanding databases
  • Evaluating phases of the same or very similar chemical composition
  • Characterizing inclusions within samples without the need to expose the inclusions
  • Encompasses different solid, liquid or gaseous phases within the inclusion
  • Analyzing archived samples that have been mounted under glass cover slips
  • Residual pressure and stress within a sample by looking at shifts in the Raman peaks.

Application note:   An Exceptional View of Geological Materials with Raman Imaging

Raman imaging is a useful tool where large areas of the sample can be analyzed and still preserve the spatial information. Covering larger areas of the sample provides confidence knowing that important areas are not being missed. The vast amounts of data generated by Raman imaging gives a more statistically relevant analysis of the sample.

Application note:   Visualizing Content Distribution in Tablets with Raman Imaging
There are many types of pharmaceutical formulations with  analytical problems such as identifying, verifying and evaluating the component distribution, chemical and molecular structure. This application note focuses on the rapid evaluation of whole tablets using Raman imaging to identify and evaluate the spatial distribution of the tablet components in a fast and efficient manner.

Application note:   The Analysis of Low Dose Tablets and Polymorphs Using Raman Imaging
Raman spectroscopy can distinguish between polymorphs, which are the same chemical compounds occurring in different crystalline forms. Polymorph identification is an important analysis step as these variations can affect how the drug is delivered and its therapeutic effectiveness. This application note focuses on using Raman imaging for evaluating the spatial distribution of active pharmaceutical ingredients in lower concentration tablets including the differentiation of polymorphs.

Application note:   Product Quality Control of a HME Co-Extrudate Using a Raman Imaging Microscope
Hot melt extrusion production is an attractive alternative to traditional methods for pharmaceutical products. Raman spectroscopy can identify and verify the presence of different components and contaminants in various formulations.

The needs of the Li-ion battery customers can be segmented into in situ and ex situ modes of analysis. In situ analysis allows researchers to follow changes in a battery cell during its charge and discharge cycles. Recent improvements in Raman sensitivity enable these changes to be imaged on a dynamic time scale. The same techniques offer significant improvements for ex situ analysis of battery components by providing more thorough sampling than traditional single point measurements. These application notes present examples showing the advantages of both modes of analysis for Li-ion electrodes.

Application note:   In Situ Raman Analysis of Lithium Ion Batteries

Application note:   Ex situ Raman Analysis of Lithium Ion Batteries

Multi-user Lab Testimonial

The University of Wisconsin-Madison has both a DXR Raman microscope and DXRxi Raman imaging microscope available in two multi-user laboratories, serving the entire university population. The laboratory users range in departments including pharmacy, geology, materials science, life sciences, and chemistry.

Hear first-hand experiences on how the DXR Raman instruments have improved these researchers' exploration and results.


DXR Raman instruments are intended for research use only, not for use in diagnostic procedures.


Thermo Scientific™ OMNIC™xi software will not only seem intuitive, but it will also look familiar. Inspired by optical, scanning electron and atomic force microscopes, this image-centric software naturally complements what you already know. The chemical and morphological analysis is built into the microscope platform rather than requiring you to learn a new spectroscopic technique or theory.

  • Spend less time looking and more time understanding. Quickly identify regions of interest and automatically find and target particles, defects, contaminants and other unique features for detailed analysis.
  • Don't wait until the end of your collection for results. Perform spectral database searches with display results in real time during data collection.
  • Never forget to collect a background again! Background collection is automatically done for you.
  • No more long collections only to find settings were not ideal. Utilize the real-time parameter tuning with immediate visual display.
  • Always be ready. Real-time visual status of the system readiness maximizes your instrument use time.