Chromosome Analysis Suite software offers an intuitive and flexible workflow for genetic analysis:
  • Specially tailored for cytogenetic use

Chromosome Analysis Suite (ChAS) was developed with input from leading experts and is customized for copy number and cytogenetics research analysis and reporting. ChAS enables you to view and summarize chromosomal aberrations across the genome. Chromosomal aberrations may include copy number gain or loss, mosaicism, or loss/absence of heterozygosity (LOH/AOH). Recent updates to the software include features to aid in exon level copy number analysis.

ChAS is comprised of three software applications:

  • Reproductive Health Research Analysis Software (RHAS) for analysis workflow setup and customization
  • Multi-Sample Viewer (MSV) for QC and copy number and variant analysis of your sample set
  • ChAS for in depth analysis of individual samples

Download ChAS 4.2     Download ChAS 4.2.1 update    Download RHAS 1.0

The release of ChAS 4.2 enhances the analysis experience by:

  • NEW Automatic prioritization of copy number segments in order of relevance based on your defined criteria
    • Score and tier-based criteria options
  • NEW Automatic result file creation no longer requiring manual intervention
  • Software update 4.2.1 enables direct linking to the recently released DECIPHER hg38 database
Chromosome Analysis Suite 4.2 (ChAS 4.2)

ChAS training videos

Compare your current analysis pipeline and see what features you may be missing out on

In addition to the support for ChAS offered from our technical teams, we now offer these convenient on-demand training videos. They are easy to follow, cover a wide range of topics, and are each designed to be viewed in only 20-40 minutes. Whether you’re a seasoned expert looking for a refresher or a potential new user to ChAS, the videos offer helpful training when your schedule allows.

Compare your current CMA software to ChAS by viewing the featured module below. Then access all modules using the button below.

Access all modules

ChAS training modules

  1. ChAS Software Installation 
  2. Analysis Workflow Overview
  3. Overview of the ChAS Browser 
  4. CNV and LOH Data Review 
  5. ChAS Database Overview
  6. CytoRegions and Overlap Map: AED and BED Files 
  7. Sample case complete analysis workflow
  8. ChAS version 4.2.1 features

Additional software files and sample data sets

Analysis files

ChAS requires sets of analysis files to create and visualize copy number, LOH, and genotyping data files for CytoScan Cytogenetics Suite, OncoScan CNV Plus Assay, and OncoScan CNV Assay arrays.

To download these files into the appropriate ChAS library folder from within the software, use the Help>Update Library and Annotation Files functionality or download them from the Analysis Workflow using Utilities>Download Library Files. Within RHAS you can download them from Preferences>Download Library Files.

Alternatively, to copy the files into your ChAS Library folder manually, download the Analysis Files.zip to the data analysis workstation, extract the zip archive, open the folder containing the files, copy all of the files, and paste them into the ChAS Library, using the instructions in the ChAS User Guide located in the ChAS software zip package.

Sample data sets

The sample data zip package for the different array types includes data files and a description key document.

CytoScan HD Array

OncoScan CNV Plus Assay

Download ChAS 4.2