SUM_Main_Final-showcase

The Thermo Scientific HyPerforma Single-Use Mixer (S.U.M.) has been designed using a proven engineered mixer platform design and offers a more ergonomic and efficient user experience for upstream and downstream mixing applications. The complete line of HyPerforma S.U.M.s includes 50, 100, 200, 500, 1,000 and 2,000 L sizes that helps ensure consistent scalability while providing a number of application usages from powder media and buffer hydration to advanced downstream harvest and intermediate pooling steps.

The Touchscreen Console for HyPerforma S.U.M. provides unsurpassed integrated sensor monitoring, automated mixing recipes, and pump control for pH and saline titration and for automatic fill and harvest of the S.U.M.

In bioproduction, mixing technologies can be found completing vital tasks across the entire workflow, and thus mixing equipment should be selected to best meet the demands of an increasingly complex industry. Enhance your upstream and downstream processes with the Touchscreen Console for S.U.M. The Touchscreen Console provides the user with advanced sensor monitoring and user-defined automated mixing recipes. The Touchscreen Console will help improve yields, shorten process times, and optimize workflows—without compromise.

Key advantages
Customized module user interface allows for unsurpassed process monitoring and automation. Modules include:

  • Agitation (mixing rpm)
  • Mass (utilization of load cell readings)
  • Temperature (1 or 2 RTDs)
  • Timer
  • pH (1 or 2 readings)
  • Conductivity (1 or 2 readings)
  • BPC pressure (automated BPC air fill)
  • Liquid pressure (Pump control based on liquid pressure in lineset)
  • Pump control (up to four pumps, used for fill, harvest, and bolus control
  • Automated and metered
  • Fill and harvest
  • Recipes (user defined process automation)
  • Auxiliary input

System highlights

  • Touchscreen Console – Enhanced user interface provides monitoring and control of the mixing parameters
  • Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BPC
  • Mixer vessel offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom) for integration with external temperature control unit
  • Single-use contact surfaces for mixing, venting, and temperature sensing
  • Conical vessel bottom for better drainage and less hold-up volume
  • Open cart frame for easier cleaning
  • Load cells weighing systems enable accurate batch weight monitoring

Key features

  • Adjustable powder hanger that fits 1 kg, 5 kg, 25 kg Powdertainer BPCs
  • Cable management system provides greater organization for electrical cables, tubing and line sets while making the unit easier to clean
  • Dedicated adjustable tool holder keeps necessary tools available for convenience
areas-application

Critical upstream application steps:

  • Media preparation
  • Final formulation steps
  • Buffer preparation
  • Harvest vessels
  • Large-volume mixing (up to 2,000 L)

Critical downstream application steps:

  • Pooling and liquid transfer
  • Product suspension
  • Mixing and storing multiple batches
  • Buffer preparation
  • Viral inactivation
  • Acid/base titration

In bioproduction, mixing technologies can be found completing vital tasks across the entire workflow, and thus mixing equipment should be selected to best meet the demands of an increasingly complex industry. Enhance your upstream and downstream processes with the Touchscreen Console for S.U.M. The Touchscreen Console provides the user with advanced sensor monitoring and user-defined automated mixing recipes. The Touchscreen Console will help improve yields, shorten process times, and optimize workflows—without compromise.

Key advantages
Customized module user interface allows for unsurpassed process monitoring and automation. Modules include:

  • Agitation (mixing rpm)
  • Mass (utilization of load cell readings)
  • Temperature (1 or 2 RTDs)
  • Timer
  • pH (1 or 2 readings)
  • Conductivity (1 or 2 readings)
  • BPC pressure (automated BPC air fill)
  • Liquid pressure (Pump control based on liquid pressure in lineset)
  • Pump control (up to four pumps, used for fill, harvest, and bolus control
  • Automated and metered
  • Fill and harvest
  • Recipes (user defined process automation)
  • Auxiliary input

System highlights

  • Touchscreen Console – Enhanced user interface provides monitoring and control of the mixing parameters
  • Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BPC
  • Mixer vessel offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom) for integration with external temperature control unit
  • Single-use contact surfaces for mixing, venting, and temperature sensing
  • Conical vessel bottom for better drainage and less hold-up volume
  • Open cart frame for easier cleaning
  • Load cells weighing systems enable accurate batch weight monitoring

Key features

  • Adjustable powder hanger that fits 1 kg, 5 kg, 25 kg Powdertainer BPCs
  • Cable management system provides greater organization for electrical cables, tubing and line sets while making the unit easier to clean
  • Dedicated adjustable tool holder keeps necessary tools available for convenience
areas-application

Critical upstream application steps:

  • Media preparation
  • Final formulation steps
  • Buffer preparation
  • Harvest vessels
  • Large-volume mixing (up to 2,000 L)

Critical downstream application steps:

  • Pooling and liquid transfer
  • Product suspension
  • Mixing and storing multiple batches
  • Buffer preparation
  • Viral inactivation
  • Acid/base titration
Solutions utilizing the HyPerforma S.U.M. with Touchscreen Console

Related products

Ordering information

Bioprocessing resources

Click below to access products brochures, training videos, mobile apps, and more.