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          System Message

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          LOADING ...
          See other PTPN6 SIRNA Assays ›
          Gene Symbol:
          PTPN6
          Gene Name:
          protein tyrosine phosphatase, non-receptor type 6
          Gene Aliases:
          HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1
          Chromosome Location:
          Chr.12: 6946576 - 6961316 on Build GRCh38
          UniGene ID:
          Hs.63489
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 114999

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PTPN6
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_002831.5 NP_002822.2 7 1072
          NM_080548.4 NP_536858.1 7 985
          NM_080549.3 NP_536859.1 7 1072
          XM_006718994.1 XP_006719057.1 7 1129
          XM_011520988.1 XP_011519290.1 7 986
          GenBank mRNA AF178946.1 - 7 854
          AK223629.1 - 7 967
          AK290421.1 - 7 955
          AK298470.1 - 6 1238
          AK300167.1 - 6 829
          AK308230.1 - 7 1020
          AK313379.1 - 7 985
          BC002523.2 - 7 971 3140265
          BC007667.2 - 7 971 3138804
          BM006699.1 - 1 83
          BT007390.1 - 6 836
          M74903.1 - 7 913
          M77273.1 - 7 974

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          More Information


          Panther Classification:

          Molecular Function -

          protein phosphatase

          Gene Ontology Categories:

          Function(s) Process(es)

          hematopoietic progenitor cell differentiation
          negative regulation of humoral immune response mediated by circulating immunoglobulin
          protein dephosphorylation
          apoptotic process
          G-protein coupled receptor signaling pathway
          cell proliferation
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          positive regulation of phosphatidylinositol 3-kinase signaling
          peptidyl-tyrosine phosphorylation
          cell differentiation
          platelet activation
          platelet formation
          T cell costimulation
          abortive mitotic cell cycle
          positive regulation of cell adhesion mediated by integrin
          peptidyl-tyrosine dephosphorylation
          intracellular signal transduction
          megakaryocyte development
          negative regulation of T cell proliferation
          natural killer cell mediated cytotoxicity
          negative regulation of MAP kinase activity
          regulation of B cell differentiation
          negative regulation of peptidyl-tyrosine phosphorylation
          B cell receptor signaling pathway
          negative regulation of B cell receptor signaling pathway
          negative regulation of T cell receptor signaling pathway
          leukocyte migration
          regulation of release of sequestered calcium ion into cytosol
          regulation of type I interferon-mediated signaling pathway
          regulation of ERK1 and ERK2 cascade
          platelet aggregation
          regulation of G1/S transition of mitotic cell cycle
          phosphotyrosine binding
          protein tyrosine phosphatase activity
          transmembrane receptor protein tyrosine phosphatase activity
          protein binding
          SH3 domain binding
          protein kinase binding
          SH2 domain binding

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