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          System Message

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          LOADING ...
          See other FOXP3 SIRNA Assays ›
          Gene Symbol:
          FOXP3
          Gene Name:
          forkhead box P3
          Gene Aliases:
          AIID, DIETER, IPEX, JM2, PIDX, XPID
          Chromosome Location:
          Chr.X: 49250436 - 49266505 on Build GRCh38
          UniGene ID:
          Hs.247700
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 115971

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: FOXP3
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001114377.1 NP_001107849.1 11 1657
          NM_014009.3 NP_054728.2 12 1762
          XM_006724533.2 XP_006724596.2 11 1937
          XM_011543916.2 XP_011542218.1 11 3367
          XM_017029565.1 XP_016885054.1 13 3223
          XM_017029566.1 XP_016885055.1 12 3187
          XM_017029567.1 XP_016885056.1 10 1762
          GenBank mRNA AF277993.1 - 12 1762

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          B cell homeostasis
          cytokine production
          myeloid cell homeostasis
          CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment
          T cell mediated immunity
          tolerance induction to self antigen
          regulation of T cell anergy
          positive regulation of T cell anergy
          negative regulation of chronic inflammatory response
          negative regulation of T cell cytokine production
          positive regulation of peripheral T cell tolerance induction
          chromatin remodeling
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          negative regulation of cell proliferation
          response to virus
          negative regulation of histone deacetylation
          negative regulation of NF-kappaB transcription factor activity
          negative regulation of interferon-gamma production
          negative regulation of interleukin-10 production
          negative regulation of interleukin-17 production
          negative regulation of interleukin-2 production
          negative regulation of interleukin-4 production
          negative regulation of interleukin-5 production
          negative regulation of interleukin-6 production
          negative regulation of tumor necrosis factor production
          positive regulation of interleukin-4 production
          negative regulation of CREB transcription factor activity
          positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
          positive regulation of transforming growth factor beta1 production
          positive regulation of immature T cell proliferation in thymus
          positive regulation of histone acetylation
          negative regulation of histone acetylation
          negative regulation of cytokine biosynthetic process
          T cell activation
          negative regulation of T cell proliferation
          T cell homeostasis
          negative regulation of sequence-specific DNA binding transcription factor activity
          negative regulation of interferon-gamma biosynthetic process
          negative regulation of interleukin-2 biosynthetic process
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of activated T cell proliferation
          negative regulation of isotype switching to IgE isotypes
          regulation of isotype switching to IgG isotypes
          negative regulation of cytokine secretion
          negative regulation of immune response
          T cell receptor signaling pathway
          negative regulation of T-helper 17 cell differentiation
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          core promoter binding
          transcription factor activity, sequence-specific DNA binding
          transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
          transcription corepressor activity
          protein binding
          histone acetyltransferase binding
          protein homodimerization activity
          histone deacetylase binding
          sequence-specific DNA binding
          metal ion binding
          NF-kappaB binding
          NFAT protein binding

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