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          System Message

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          LOADING ...
          See other MAP2K1 SIRNA Assays ›
          Gene Symbol:
          Map2k1
          Gene Name:
          mitogen-activated protein kinase kinase 1
          Gene Aliases:
          MAPKK1, MEKK1, Mek1, Prkmk1
          Chromosome Location:
          Chr.9: 64185770 - 64253605 on Build GRCm38
          UniGene ID:
          Mm.248907
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 186573

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Map2k1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_008927.3 NP_032953.1 10, 11 1380
          GenBank mRNA AB041567.1 - 10, 11 1360
          AK146233.1 - 10, 11 1370
          AK146931.1 - 10, 11 1373
          AK154793.1 - 10, 11 1407
          AK165664.1 - 9, 10 914
          AK165894.1 - 10, 11 1381
          AK167336.1 - 10, 11 1347
          BC051137.1 - 10, 11 1199
          BC054754.1 - 10, 11 1159 6411664
          L02526.1 - 10, 11 1107

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_031643, D14591, Z16415, X62313, BC089772, and others.

          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          activation of MAPK activity
          regulation of protein phosphorylation
          regulation of vascular smooth muscle contraction
          protein phosphorylation
          response to oxidative stress
          cell cycle arrest
          mitotic nuclear division
          cell proliferation
          negative regulation of cell proliferation
          positive regulation of gene expression
          phosphorylation
          neuron differentiation
          keratinocyte differentiation
          positive regulation of cell migration
          melanosome transport
          regulation of stress-activated MAPK cascade
          positive regulation of transcription elongation from RNA polymerase II promoter
          negative regulation of homotypic cell-cell adhesion
          peptidyl-tyrosine dephosphorylation
          positive regulation of GTPase activity
          positive regulation of cell differentiation
          positive regulation of Ras protein signal transduction
          vesicle transport along microtubule
          Golgi inheritance
          response to axon injury
          regulation of axon regeneration
          neuron projection morphogenesis
          cell motility
          positive regulation of axonogenesis
          protein heterooligomerization
          response to glucocorticoid
          lung morphogenesis
          trachea formation
          epithelial cell proliferation involved in lung morphogenesis
          placenta blood vessel development
          labyrinthine layer development
          ERK1 and ERK2 cascade
          positive regulation of protein serine/threonine kinase activity
          regulation of Golgi inheritance
          cellular senescence
          mitophagy in response to mitochondrial depolarization
          regulation of early endosome to late endosome transport
          nucleotide binding
          protein kinase activity
          protein serine/threonine kinase activity
          MAP kinase kinase activity
          protein serine/threonine/tyrosine kinase activity
          protein tyrosine kinase activity
          receptor signaling protein tyrosine phosphatase activity
          protein binding
          ATP binding
          protein C-terminus binding
          kinase activity
          transferase activity
          transferase activity, transferring phosphorus-containing groups
          Ras GTPase binding
          protein kinase binding
          mitogen-activated protein kinase kinase kinase binding
          protein serine/threonine kinase activator activity
          protein N-terminus binding

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