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          System Message

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          LOADING ...
          See other PLK1 SIRNA Assays ›
          Gene Symbol:
          PLK1
          Gene Name:
          polo like kinase 1
          Gene Aliases:
          PLK, STPK13
          Chromosome Location:
          Chr.16: 23678772 - 23690367 on Build GRCh38
          UniGene ID:
          Hs.592049
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 213947

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PLK1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_005030.5 NP_005021.2 4 945
          GenBank mRNA AB209179.1 - 3 2804
          AK303263.1 - 5 561
          AK308276.1 - 5 802
          AK313227.1 - 4 869
          BC002369.2 - 4 837 2822226
          BC003002.1 - 4 815 2823623
          BC014846.1 - 4 790 3854860
          L19559.1 - 4 847
          U01038.1 - 4 847
          X73458.1 - 4 861
          X75932.1 - 4 847

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_017100, BC083926, U10188.
          This siRNA also targets the following transcripts in Mouse: NM_011121, AK148076, BC006880, AK134045, L19558, and others.

          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase protein modifying enzyme

          Gene Ontology Categories:

          Function(s) Process(es)

          mitotic sister chromatid segregation
          G2/M transition of mitotic cell cycle
          negative regulation of transcription from RNA polymerase II promoter
          mitotic cytokinesis
          cytokinesis
          microtubule bundle formation
          protein phosphorylation
          sister chromatid cohesion
          mitotic nuclear division
          mitotic nuclear envelope disassembly
          mitotic spindle assembly checkpoint
          regulation of mitotic cell cycle
          cell proliferation
          positive regulation of peptidyl-threonine phosphorylation
          female meiosis chromosome segregation
          protein ubiquitination
          peptidyl-serine phosphorylation
          regulation of mitotic metaphase/anaphase transition
          anaphase-promoting complex-dependent catabolic process
          G2 DNA damage checkpoint
          protein destabilization
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process
          protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          negative regulation of apoptotic process
          regulation of protein binding
          homologous chromosome segregation
          establishment of protein localization
          negative regulation of cyclin-dependent protein serine/threonine kinase activity
          positive regulation of proteolysis
          centrosome organization
          positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
          regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
          positive regulation of ubiquitin-protein transferase activity
          regulation of cell cycle
          synaptonemal complex disassembly
          protein localization to chromatin
          positive regulation of protein localization to nucleus
          regulation of mitotic spindle assembly
          regulation of cell cycle G2/M phase transition
          positive regulation of ubiquitin protein ligase activity
          protein kinase activity
          protein serine/threonine kinase activity
          protein binding
          ATP binding
          microtubule binding
          anaphase-promoting complex binding
          kinase activity
          protein kinase binding

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