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          System Message

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          LOADING ...
          See other DNMT1 SIRNA Assays ›
          Gene Symbol:
          Dnmt1
          Gene Name:
          DNA (cytosine-5-)-methyltransferase 1
          Gene Aliases:
          -
          Chromosome Location:
          Chr.8: 21922515 - 21968495 on Build Rnor_6.0
          UniGene ID:
          Rn.6955
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          siRNA ID 46874

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Dnmt1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_053354.3 NP_445806.3 2 176
          GenBank mRNA AB012214.1 - 2 160
          AF116344.1 - 2 214
          D64060.1 - 2 48
          DV214494.1 - 2 142

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: NM_001199431, NM_010066, NM_001199433, NM_001199432, AF036009, and others.

          Panther Classification:

          Molecular Function -

          DNA metabolism protein DNA methyltransferase nucleic acid metabolism protein

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          DNA methylation
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          brain development
          aging
          response to heat
          response to toxic substance
          response to organic substance
          response to ionizing radiation
          maintenance of DNA methylation
          response to lead ion
          DNA methylation on cytosine within a CG sequence
          regulation of gene expression
          positive regulation of gene expression
          response to activity
          gene silencing
          chromatin modification
          neuron differentiation
          response to caffeine
          response to nutrient levels
          response to estradiol
          response to lipopolysaccharide
          DNA methylation on cytosine
          response to vitamin A
          response to testosterone
          cellular response to platelet-derived growth factor stimulus
          response to antidepressant
          regulation of cell proliferation
          response to drug
          DNA hypermethylation
          response to ethanol
          negative regulation of transcription, DNA-templated
          S-adenosylhomocysteine metabolic process
          S-adenosylmethioninamine metabolic process
          S-adenosylmethionine metabolic process
          positive regulation of histone H3-K4 methylation
          negative regulation of histone H3-K9 methylation
          cellular response to amino acid stimulus
          cellular response to lead ion
          cellular response to transforming growth factor beta stimulus
          C-5 methylation of cytosine
          cellular response to nerve growth factor stimulus
          DNA binding
          chromatin binding
          double-stranded DNA binding
          RNA binding
          DNA (cytosine-5-)-methyltransferase activity
          protein binding
          transcription factor binding
          methyltransferase activity
          zinc ion binding
          methyl-CpG binding
          S-adenosylmethionine-dependent methyltransferase activity
          DNA-methyltransferase activity
          protein domain specific binding
          estrogen receptor binding
          histone deacetylase binding
          unmethylated CpG binding
          DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

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