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          System Message

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          LOADING ...
          See other ARRB1 SIRNA Assays ›
          Gene Symbol:
          ARRB1
          Gene Name:
          arrestin beta 1
          Gene Aliases:
          ARB1, ARR1
          Chromosome Location:
          Chr.11: 75260122 - 75351831 on Build GRCh38
          UniGene ID:
          Hs.503284
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 5214

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ARRB1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_004041.4 NP_004032.2 16 1424
          NM_020251.3 NP_064647.1 15 1400
          XM_011545034.2 XP_011543336.1 17 1308
          XM_011545035.2 XP_011543337.1 16 1284
          XM_017017750.1 XP_016873239.1 18 1380
          XM_017017751.1 XP_016873240.1 17 1356
          XM_017017752.1 XP_016873241.1 17 1336
          XM_017017753.1 XP_016873242.1 17 1400
          XM_017017754.1 XP_016873243.1 16 1312
          GenBank mRNA AF084040.1 - 16 1200
          AF084940.1 - 15 1176
          AK289718.1 - 16 1254
          BC003636.2 - 16 1277 3604829
          FJ348262.1 - 15 1176

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_012910, XM_006229740, XM_006229739, XM_006229736, XM_006229741, and others.
          This siRNA also targets the following transcripts in Mouse: NM_177231, NM_178220, AK036421, AK090090, AK147508, and others.

          Panther Classification:

          Molecular Function -

          scaffold/adaptor protein

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPK activity
          positive regulation of protein phosphorylation
          G-protein coupled receptor internalization
          positive regulation of receptor internalization
          transcription from RNA polymerase II promoter
          apoptotic process
          phototransduction
          protein transport
          protein ubiquitination
          platelet activation
          negative regulation of protein ubiquitination
          positive regulation of protein ubiquitination
          negative regulation of NF-kappaB transcription factor activity
          positive regulation of protein binding
          negative regulation of interleukin-6 production
          negative regulation of interleukin-8 production
          positive regulation of peptidyl-serine phosphorylation
          negative regulation of GTPase activity
          positive regulation of smooth muscle cell apoptotic process
          positive regulation of Rho protein signal transduction
          positive regulation of histone acetylation
          positive regulation of insulin secretion involved in cellular response to glucose stimulus
          response to antidepressant
          follicle-stimulating hormone signaling pathway
          stress fiber assembly
          negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
          proteasome-mediated ubiquitin-dependent protein catabolic process
          positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
          positive regulation of GTPase activity
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of ERK1 and ERK2 cascade
          positive regulation of ERK1 and ERK2 cascade
          positive regulation of histone H4 acetylation
          histone acetyltransferase activity
          enzyme inhibitor activity
          GTPase activator activity
          insulin-like growth factor receptor binding
          protein binding
          transcription factor binding
          estrogen receptor binding
          mitogen-activated protein kinase kinase binding
          ubiquitin protein ligase binding
          alpha-1A adrenergic receptor binding
          alpha-1B adrenergic receptor binding
          angiotensin receptor binding
          follicle-stimulating hormone receptor binding
          V2 vasopressin receptor binding
          AP-2 adaptor complex binding
          clathrin adaptor activity
          cysteine-type endopeptidase inhibitor activity involved in apoptotic process
          transcription regulatory region DNA binding
          ion channel binding
          protein phosphorylated amino acid binding

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          Host server : magellan-search-green-55658555d6-pnd5g:80/100.66.79.83:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
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