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          System Message

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          LOADING ...
          See other CDKN2A SIRNA Assays ›
          Gene Symbol:
          Cdkn2a
          Gene Name:
          cyclin-dependent kinase inhibitor 2A
          Gene Aliases:
          Arf, INK4A, MTS1, p16, p16Cdkn2a, p19ARF
          Chromosome Location:
          Chr.5: 107823323 - 107832405 on Build Rnor_6.0
          UniGene ID:
          Rn.48717
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          siRNA ID 53734

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 286.00
          Your Price
          Online offer: 277.65
          277.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Cdkn2a
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_031550.1 NP_113738.1 2 467
          GenBank mRNA AF474974.1 - 508
          AF474975.1 - 508
          AF474976.1 - 2 443
          AF474977.1 - 2 434
          AY679727.1 - 508
          AY679728.1 - 2 443
          L81167.1 - 2 467

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          regulation of cyclin-dependent protein serine/threonine kinase activity
          G1/S transition of mitotic cell cycle
          protein polyubiquitination
          negative regulation of cell-matrix adhesion
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          rRNA processing
          negative regulation of protein kinase activity
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          cell cycle arrest
          Ras protein signal transduction
          aging
          cell aging
          negative regulation of cell proliferation
          epidermis development
          apoptotic mitochondrial changes
          rRNA transcription
          response to organic substance
          response to organonitrogen compound
          regulation of G2/M transition of mitotic cell cycle
          regulation of gene expression
          response to organic cyclic compound
          cerebellum development
          negative regulation of cell growth
          negative regulation of B cell proliferation
          regulation of protein stability
          protein destabilization
          negative regulation of NF-kappaB transcription factor activity
          negative regulation of protein binding
          negative regulation of immature T cell proliferation in thymus
          positive regulation of protein sumoylation
          negative regulation of mammary gland epithelial cell proliferation
          positive regulation of smooth muscle cell apoptotic process
          somatic stem cell population maintenance
          senescence-associated heterochromatin focus assembly
          negative regulation of phosphorylation
          response to drug
          glucose homeostasis
          positive regulation of apoptotic process
          positive regulation of DNA damage response, signal transduction by p53 class mediator
          negative regulation of cyclin-dependent protein serine/threonine kinase activity
          negative regulation of cell cycle
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          regulation of nucleocytoplasmic transport
          regulation of protein export from nucleus
          somatic stem cell division
          protein stabilization
          positive regulation of sequence-specific DNA binding transcription factor activity
          negative regulation of ubiquitin-protein transferase activity
          positive regulation of apoptotic process involved in mammary gland involution
          cellular response to hydrogen peroxide
          protein K63-linked ubiquitination
          positive regulation of cell cycle arrest
          cellular senescence
          replicative senescence
          positive regulation of protein localization to nucleus
          positive regulation of signal transduction by p53 class mediator
          regulation of apoptotic DNA fragmentation
          negative regulation of proteolysis involved in cellular protein catabolic process
          negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          positive regulation of macrophage apoptotic process
          positive regulation of cellular senescence
          p53 binding
          DNA binding
          transcription factor activity, sequence-specific DNA binding
          cyclin-dependent protein serine/threonine kinase inhibitor activity
          transcription factor binding
          protein kinase binding
          poly(A) RNA binding
          NF-kappaB binding
          ubiquitin-protein transferase inhibitor activity
          MDM2/MDM4 family protein binding

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