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          System Message

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          LOADING ...
          See other PTPN11 SIRNA Assays ›
          Gene Symbol:
          Ptpn11
          Gene Name:
          protein tyrosine phosphatase, non-receptor type 11
          Gene Aliases:
          2700084A17Rik, AW536184, PTP1D, PTP2C, SAP-2, SH-PTP2, SH-PTP3, SHP-2, Shp2, Syp
          Chromosome Location:
          Chr.5: 121130533 - 121191397 on Build GRCm38
          UniGene ID:
          Mm.8681
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 68983

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Ptpn11
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001109992.1 NP_001103462.1 7 992
          NM_011202.3 NP_035332.1 7 992
          GenBank mRNA AK147354.1 - 7 963
          AK159501.1 - 7 992
          AK159587.1 - 7 992
          AK163809.1 - 4 420
          BC057398.1 - 7 924 6409640
          BC059278.1 - 7 970 2866038
          D84372.1 - 7 868

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_001177593, NM_013088, D83016, U05963, U09307.

          Panther Classification:

          Molecular Function -

          protein phosphatase

          Gene Ontology Categories:

          Function(s) Process(es)

          DNA damage checkpoint
          activation of MAPK activity
          protein dephosphorylation
          lipid metabolic process
          triglyceride metabolic process
          epidermal growth factor receptor signaling pathway
          integrin-mediated signaling pathway
          axonogenesis
          brain development
          heart development
          hormone-mediated signaling pathway
          positive regulation of signal transduction
          dephosphorylation
          platelet formation
          microvillus organization
          abortive mitotic cell cycle
          regulation of cell adhesion mediated by integrin
          negative regulation of cell adhesion mediated by integrin
          multicellular organism growth
          organ growth
          peptidyl-tyrosine dephosphorylation
          megakaryocyte development
          atrioventricular canal development
          ERBB signaling pathway
          regulation of multicellular organism growth
          hormone metabolic process
          glucose homeostasis
          positive regulation of mitotic cell cycle
          negative regulation of insulin secretion
          regulation of protein export from nucleus
          positive regulation of hormone secretion
          negative regulation of hormone secretion
          platelet-derived growth factor receptor signaling pathway
          neurotrophin TRK receptor signaling pathway
          ephrin receptor signaling pathway
          multicellular organismal reproductive process
          genitalia development
          inner ear development
          homeostasis of number of cells within a tissue
          negative regulation of cortisol secretion
          negative regulation of growth hormone secretion
          face morphogenesis
          intestinal epithelial cell migration
          positive regulation of ERK1 and ERK2 cascade
          positive regulation of glucose import in response to insulin stimulus
          phosphoprotein phosphatase activity
          protein tyrosine phosphatase activity
          non-membrane spanning protein tyrosine phosphatase activity
          SH3/SH2 adaptor activity
          insulin receptor binding
          protein binding
          hydrolase activity
          phosphatase activity
          protein domain specific binding
          receptor tyrosine kinase binding
          D1 dopamine receptor binding
          phospholipase binding
          insulin receptor substrate binding
          peptide hormone receptor binding

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