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          System Message

          OKCancel
          LOADING ...
          See other PARK7 SIRNA Assays ›
          Gene Symbol:
          Park7
          Gene Name:
          Parkinson disease (autosomal recessive, early onset) 7
          Gene Aliases:
          DJ-1, Dj1
          Chromosome Location:
          Chr.4: 150897133 - 150914432 on Build GRCm38
          UniGene ID:
          Mm.277349
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 75160

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Park7
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_020569.3 NP_065594.2 4 386
          GenBank mRNA AB015652.1 - 4 333
          AK146368.1 - 4 298
          AK153948.1 - 4 343
          AK168341.1 - 4 316
          BC002187.1 - 4 292 3487763
          CA456587.1 - 4 424

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_001277250, NM_001277251, NM_001277249, NM_001277253, NM_001277252, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of protein phosphorylation
          synaptic transmission, dopaminergic
          negative regulation of protein kinase activity
          proteolysis
          protein deglycosylation
          autophagy
          inflammatory response
          response to oxidative stress
          mitochondrion organization
          single fertilization
          cell proliferation
          adult locomotory behavior
          detoxification of copper ion
          positive regulation of gene expression
          negative regulation of gene expression
          enzyme active site formation via L-cysteine sulfinic acid
          methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
          lactate biosynthetic process
          negative regulation of protein ubiquitination
          negative regulation of protein binding
          negative regulation of proteasomal ubiquitin-dependent protein catabolic process
          positive regulation of interleukin-8 production
          positive regulation of peptidyl-serine phosphorylation
          negative regulation of protein sumoylation
          cellular response to oxidative stress
          cellular response to reactive oxygen species
          cellular response to glyoxal
          negative regulation of protein catabolic process
          response to hydrogen peroxide
          hydrogen peroxide metabolic process
          negative regulation of apoptotic process
          regulation of neuron apoptotic process
          negative regulation of neuron apoptotic process
          positive regulation of transcription from RNA polymerase II promoter
          glycolate biosynthetic process
          negative regulation of protein export from nucleus
          regulation of inflammatory response
          detoxification of mercury ion
          protein stabilization
          positive regulation of sequence-specific DNA binding transcription factor activity
          negative regulation of ubiquitin-protein transferase activity
          dopamine uptake involved in synaptic transmission
          regulation of mitochondrial membrane potential
          membrane depolarization
          oxidation-reduction process
          membrane hyperpolarization
          negative regulation of cell death
          regulation of androgen receptor signaling pathway
          cellular response to hydrogen peroxide
          positive regulation of protein homodimerization activity
          positive regulation of protein localization to nucleus
          negative regulation of neuron death
          positive regulation of superoxide dismutase activity
          negative regulation of protein acetylation
          positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          positive regulation of mitochondrial electron transport, NADH to ubiquinone
          negative regulation of protein K48-linked deubiquitination
          negative regulation of TRAIL-activated apoptotic signaling pathway
          positive regulation of pyrroline-5-carboxylate reductase activity
          positive regulation of tyrosine 3-monooxygenase activity
          positive regulation of dopamine biosynthetic process
          glyoxal catabolic process
          positive regulation of L-dopa biosynthetic process
          positive regulation of L-dopa decarboxylase activity
          negative regulation of oxidative stress-induced cell death
          negative regulation of oxidative stress-induced neuron death
          negative regulation of hydrogen peroxide-induced cell death
          negative regulation of hydrogen peroxide-induced neuron death
          negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
          negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
          positive regulation of reactive oxygen species biosynthetic process
          negative regulation of ubiquitin-specific protease activity
          positive regulation of oxidative phosphorylation uncoupler activity
          positive regulation of transcription regulatory region DNA binding
          positive regulation of androgen receptor activity
          negative regulation of extrinsic apoptotic signaling pathway
          negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
          transcription coactivator activity
          RNA binding
          mRNA binding
          histone deacetylase activity
          receptor binding
          copper ion binding
          protein binding
          transcription factor binding
          peptidase activity
          protein-N-terminal asparagine amidohydrolase activity
          UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
          CoA hydrolase activity
          superoxide dismutase copper chaperone activity
          oxidoreductase activity, acting on peroxide as acceptor
          hydrolase activity
          iprodione amidohydrolase activity
          (3,5-dichlorophenylurea)acetate amidohydrolase activity
          glyoxalase III activity
          enzyme binding
          kinase binding
          cytokine binding
          4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity
          didemethylisoproturon amidohydrolase activity
          N-isopropylacetanilide amidohydrolase activity
          N-cyclohexylformamide amidohydrolase activity
          2-oxoglutaryl-CoA thioesterase activity
          2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity
          isonicotinic acid hydrazide hydrolase activity
          cis-aconitamide amidase activity
          gamma-N-formylaminovinylacetate hydrolase activity
          3-isopropylbut-3-enoyl-CoA thioesterase activity
          tyrosine 3-monooxygenase activator activity
          L-dopa decarboxylase activator activity
          identical protein binding
          protein homodimerization activity
          N2-acetyl-L-lysine deacetylase activity
          O-succinylbenzoate synthase activity
          indoleacetamide hydrolase activity
          N-acetylcitrulline deacetylase activity
          small protein activating enzyme binding
          ubiquitin-like protein conjugating enzyme binding
          glutaryl-CoA hydrolase activity
          mercury ion binding
          N-acetylgalactosamine-6-phosphate deacetylase activity
          acyl-CoA hydrolase activity
          androgen receptor binding
          peroxiredoxin activity
          diacetylchitobiose deacetylase activity
          chitooligosaccharide deacetylase activity
          repressing transcription factor binding
          scaffold protein binding
          cupric ion binding
          cuprous ion binding
          ubiquitin-specific protease binding
          glyoxalase (glycolic acid-forming) activity

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          Host server : magellan-search-blue-55ff9ddd88-hrqnb:80/100.66.75.244:80.
          git-commit: d366ff9721d93504b2ac26a183b2b3e3d0e7d9ec
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.42.0-2026.01.03-1.0