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          System Message

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          LOADING ...
          See other NF1 SIRNA Assays ›
          Gene Symbol:
          NF1
          Gene Name:
          neurofibromin 1
          Gene Aliases:
          NFNS, VRNF, WSS
          Chromosome Location:
          Chr.17: 31094927 - 31377677 on Build GRCh38
          UniGene ID:
          Hs.113577
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 8089

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: NF1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000267.3 NP_000258.1 2 467
          NM_001042492.2 NP_001035957.1 2 467
          NM_001128147.2 NP_001121619.1 2 467
          XM_005257983.2 XP_005258040.1 2 417
          XM_005257984.2 XP_005258041.1 2 417
          XM_006721922.2 XP_006721985.1 2 417
          XM_006721924.2 XP_006721987.1 2 417
          XM_006721925.2 XP_006721988.1 2 417
          XM_006721926.3 XP_006721989.1 2 417
          XM_011524852.2 XP_011523154.1 2 417
          XM_011524857.2 XP_011523159.1 2 417
          XM_017024689.1 XP_016880178.1 2 417
          XM_017024690.1 XP_016880179.1 2 417
          GenBank mRNA AK289936.1 - 2 417
          BC144643.1 - 2 186
          D12625.1 - 2 467
          D42072.1 - 2 149
          DA299151.1 - 2 417
          DB094344.1 - 2 417
          M82814.1 - 2 295
          M89914.1 - 2 281

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_012609, D45201.
          This siRNA also targets the following transcripts in Mouse: NM_010897, AK085050, BB660074, L10370.

          Panther Classification:

          Molecular Function -

          GTPase-activating protein

          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          osteoblast differentiation
          metanephros development
          response to hypoxia
          liver development
          negative regulation of endothelial cell proliferation
          positive regulation of endothelial cell proliferation
          regulation of cell-matrix adhesion
          negative regulation of cell-matrix adhesion
          negative regulation of protein kinase activity
          cell communication
          Ras protein signal transduction
          negative regulation of neuroblast proliferation
          brain development
          peripheral nervous system development
          heart development
          skeletal muscle tissue development
          visual learning
          extrinsic apoptotic signaling pathway via death domain receptors
          regulation of gene expression
          Schwann cell development
          phosphatidylinositol 3-kinase signaling
          negative regulation of angiogenesis
          spinal cord development
          amygdala development
          forebrain astrocyte development
          neural tube development
          cerebral cortex development
          myelination in peripheral nervous system
          actin cytoskeleton organization
          extracellular matrix organization
          collagen fibril organization
          adrenal gland development
          negative regulation of cell migration
          regulation of synaptic transmission, GABAergic
          cellular response to heat
          negative regulation of Rac protein signal transduction
          wound healing
          negative regulation of transcription factor import into nucleus
          positive regulation of apoptotic process
          regulation of GTPase activity
          negative regulation of MAP kinase activity
          negative regulation of MAPK cascade
          pigmentation
          positive regulation of neuron apoptotic process
          regulation of blood vessel endothelial cell migration
          positive regulation of GTPase activity
          regulation of bone resorption
          negative regulation of osteoclast differentiation
          regulation of glial cell differentiation
          positive regulation of adenylate cyclase activity
          regulation of angiogenesis
          negative regulation of Ras protein signal transduction
          negative regulation of neurotransmitter secretion
          negative regulation of fibroblast proliferation
          regulation of long-term neuronal synaptic plasticity
          sympathetic nervous system development
          camera-type eye morphogenesis
          negative regulation of astrocyte differentiation
          negative regulation of oligodendrocyte differentiation
          smooth muscle tissue development
          artery morphogenesis
          forebrain morphogenesis
          cognition
          gamma-aminobutyric acid secretion, neurotransmission
          glutamate secretion, neurotransmission
          observational learning
          regulation of long-term synaptic potentiation
          positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
          positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
          GTPase activator activity
          protein binding
          phosphatidylethanolamine binding
          phosphatidylcholine binding

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          git-commit: d366ff9721d93504b2ac26a183b2b3e3d0e7d9ec
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