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          System Message

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          LOADING ...
          See other JAK3 SIRNA Assays ›
          Gene Symbol:
          JAK3
          Gene Name:
          Janus kinase 3
          Gene Aliases:
          JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
          Chromosome Location:
          Chr.19: 17824782 - 17848071 on Build GRCh38
          UniGene ID:
          Hs.515247
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS105634
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price Contact Us
          Your Price
          Online offer:
          3062.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: JAK3
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000215.3 NP_000206.2 14 1927
          XM_005259896.3 XP_005259953.1 14 1966
          XM_011527990.1 XP_011526292.1 14 1966
          XM_011527991.2 XP_011526293.1 14 2869
          GenBank mRNA U09607.1 - 13 1922

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          adaptive immune response
          negative regulation of dendritic cell cytokine production
          protein phosphorylation
          enzyme linked receptor protein signaling pathway
          positive regulation of cytosolic calcium ion concentration
          tyrosine phosphorylation of STAT protein
          STAT protein import into nucleus
          cell migration
          peptidyl-tyrosine phosphorylation
          B cell differentiation
          negative regulation of interleukin-10 production
          negative regulation of interleukin-12 production
          intracellular signal transduction
          interleukin-4-mediated signaling pathway
          peptidyl-tyrosine autophosphorylation
          positive regulation of T cell proliferation
          positive regulation of activated T cell proliferation
          tyrosine phosphorylation of Stat5 protein
          T cell homeostasis
          positive regulation of GTPase activity
          innate immune response
          negative regulation of FasL biosynthetic process
          negative regulation of T-helper 1 cell differentiation
          positive regulation of immune response
          negative regulation of T cell activation
          positive regulation of calcium ion transport
          JAK-STAT cascade involved in growth hormone signaling pathway
          regulation of T cell apoptotic process
          negative regulation of thymocyte apoptotic process
          response to interleukin-2
          response to interleukin-4
          response to interleukin-15
          response to interleukin-9
          protein tyrosine kinase activity
          non-membrane spanning protein tyrosine kinase activity
          Ras guanyl-nucleotide exchange factor activity
          receptor binding
          protein binding
          ATP binding
          protein phosphatase binding

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