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          System Message

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          LOADING ...
          See other LIF SIRNA Assays ›
          Gene Symbol:
          LIF
          Gene Name:
          leukemia inhibitory factor
          Gene Aliases:
          CDF, DIA, HILDA, MLPLI
          Chromosome Location:
          Chr.22: 30240447 - 30246851 on Build GRCh38
          UniGene ID:
          Hs.2250
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS106046
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: LIF
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001257135.1 NP_001244064.1 2 295
          NM_002309.4 NP_002300.1 3 474
          GenBank mRNA AK315310.1 - 3 422
          BC069540.1 - 3 368 7262225
          BC093733.1 - 3 366 7939578
          BC093735.1 - 3 366 7939580
          BC143305.1 - 2 187
          CN409458.1 - 3 474
          X13967.1 - 3 362

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          More Information


          Panther Classification:

          Molecular Function -

          cytokine intercellular signal molecule

          Gene Ontology Categories:

          Function(s) Process(es)

          blood vessel remodeling
          immune response
          multicellular organism development
          embryo implantation
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          positive regulation of neuron projection development
          negative regulation of angiogenesis
          stem cell population maintenance
          organ regeneration
          positive regulation of peptidyl-serine phosphorylation
          positive regulation of peptidyl-serine phosphorylation of STAT protein
          tyrosine phosphorylation of Stat3 protein
          positive regulation of tyrosine phosphorylation of Stat1 protein
          positive regulation of tyrosine phosphorylation of Stat3 protein
          positive regulation of MAPK cascade
          positive regulation of macrophage differentiation
          negative regulation of meiotic nuclear division
          positive regulation of transcription from RNA polymerase II promoter
          decidualization
          negative regulation of hormone secretion
          lung alveolus development
          muscle organ morphogenesis
          neuron development
          astrocyte differentiation
          positive regulation of astrocyte differentiation
          leukemia inhibitory factor signaling pathway
          stem cell differentiation
          positive regulation of peptidyl-tyrosine phosphorylation
          positive regulation of corticotropin secretion
          retina development in camera-type eye
          transdifferentiation
          lung vasculature development
          lung lobe morphogenesis
          trophoblast giant cell differentiation
          spongiotrophoblast differentiation
          negative regulation of ERK1 and ERK2 cascade
          positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
          regulation of metanephric nephron tubule epithelial cell differentiation
          positive regulation of protein localization to nucleus
          positive regulation of histone H3-K27 acetylation
          regulation of RNA polymerase II regulatory region sequence-specific DNA binding
          transcription factor activity, RNA polymerase II transcription factor recruiting
          receptor binding
          cytokine activity
          leukemia inhibitory factor receptor binding
          protein binding
          growth factor activity

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