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          System Message

          OKCancel
          LOADING ...
          See other SHH SIRNA Assays ›
          Gene Symbol:
          SHH
          Gene Name:
          sonic hedgehog
          Gene Aliases:
          HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS
          Chromosome Location:
          Chr.7: 155799984 - 155812273 on Build GRCh38
          UniGene ID:
          Hs.164537
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID n273676

          Purification
          Size
          Availability Made To Order
          Catalog # 4390771
          Price 5,354.00
          Your Price
          Online offer:
          5354.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: SHH
          Interrogated Sequence Translated Protein RNADB ID Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq XM_011516480.2 XP_011514782.1
          2 2900
          GenBank mRNA AY927451.1 - LIT3479
          AY927451
          1 26

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          patterning of blood vessels
          vasculogenesis
          metanephros development
          branching involved in ureteric bud morphogenesis
          cell fate specification
          neural crest cell migration
          heart looping
          positive regulation of neuroblast proliferation
          osteoblast development
          lymphoid progenitor cell differentiation
          determination of left/right asymmetry in lateral mesoderm
          endocytosis
          smoothened signaling pathway
          positive regulation of hh target transcription factor activity
          cell-cell signaling
          pattern specification process
          ectoderm development
          neuroblast proliferation
          axon guidance
          central nervous system development
          ventral midline development
          hindgut morphogenesis
          heart development
          blood coagulation
          androgen metabolic process
          positive regulation of cell proliferation
          embryo development
          embryonic pattern specification
          polarity specification of anterior/posterior axis
          dorsal/ventral pattern formation
          oligodendrocyte development
          striated muscle tissue development
          positive regulation of skeletal muscle cell proliferation
          myotube differentiation
          intein-mediated protein splicing
          spinal cord dorsal/ventral patterning
          spinal cord motor neuron differentiation
          thalamus development
          dorsal/ventral neural tube patterning
          cerebellar granule cell precursor proliferation
          smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
          telencephalon regionalization
          establishment of cell polarity
          regulation of proteolysis
          positive regulation of Wnt signaling pathway
          lung development
          embryonic limb morphogenesis
          negative regulation of cell migration
          male genitalia development
          prostate gland development
          thyroid gland development
          forebrain development
          midbrain development
          hindbrain development
          pancreas development
          hair follicle morphogenesis
          negative regulation of proteasomal ubiquitin-dependent protein catabolic process
          T cell differentiation in thymus
          positive regulation of T cell differentiation in thymus
          positive regulation of immature T cell proliferation in thymus
          negative regulation of transcription elongation from RNA polymerase II promoter
          protein localization to nucleus
          embryonic forelimb morphogenesis
          embryonic hindlimb morphogenesis
          regulation of cell proliferation
          negative regulation of T cell proliferation
          positive regulation of protein import into nucleus
          odontogenesis of dentin-containing tooth
          regulation of odontogenesis
          embryonic digit morphogenesis
          camera-type eye development
          negative regulation of apoptotic process
          CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
          positive thymic T cell selection
          negative thymic T cell selection
          intermediate filament organization
          myoblast differentiation
          negative regulation of cell differentiation
          positive regulation of smoothened signaling pathway
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of alpha-beta T cell differentiation
          negative regulation of alpha-beta T cell differentiation
          cell development
          thymus development
          embryonic digestive tract morphogenesis
          embryonic foregut morphogenesis
          positive regulation of skeletal muscle tissue development
          organ formation
          neuron fate commitment
          embryonic skeletal system development
          positive regulation of oligodendrocyte differentiation
          branching morphogenesis of an epithelial tube
          inner ear development
          formation of anatomical boundary
          stem cell development
          positive regulation of striated muscle cell differentiation
          positive regulation of cell division
          Bergmann glial cell differentiation
          palate development
          canonical Wnt signaling pathway
          limb bud formation
          lung epithelium development
          trachea morphogenesis
          branching involved in salivary gland morphogenesis
          bud outgrowth involved in lung branching
          right lung development
          left lung development
          lung lobe morphogenesis
          lung-associated mesenchyme development
          primary prostatic bud elongation
          prostate epithelial cord elongation
          salivary gland cavitation
          epithelial cell proliferation involved in salivary gland morphogenesis
          regulation of prostatic bud formation
          epithelial-mesenchymal signaling involved in prostate gland development
          positive regulation of epithelial cell proliferation involved in prostate gland development
          regulation of mesenchymal cell proliferation involved in prostate gland development
          mesenchymal smoothened signaling pathway involved in prostate gland development
          artery development
          mesenchymal cell proliferation involved in lung development
          somite development
          positive regulation of sclerotome development
          cellular response to lithium ion
          dopaminergic neuron differentiation
          renal system development
          metanephric mesenchymal cell proliferation involved in metanephros development
          multicellular structure septum development
          negative regulation of canonical Wnt signaling pathway
          negative regulation of cholesterol efflux
          apoptotic signaling pathway
          regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
          regulation of protein localization to nucleus
          negative regulation of dopaminergic neuron differentiation
          negative regulation of ureter smooth muscle cell differentiation
          positive regulation of ureter smooth muscle cell differentiation
          negative regulation of kidney smooth muscle cell differentiation
          positive regulation of kidney smooth muscle cell differentiation
          positive regulation of mesenchymal cell proliferation involved in ureter development
          negative regulation of mesenchymal cell apoptotic process
          glycoprotein binding
          patched binding
          calcium ion binding
          protein binding
          glycosaminoglycan binding
          peptidase activity
          zinc ion binding
          morphogen activity
          laminin-1 binding

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          Host server : magellan-search-green-55658555d6-72rkq:80/100.66.79.224:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline