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          System Message

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          LOADING ...
          See other WRN SIRNA Assays ›
          Gene Symbol:
          WRN
          Gene Name:
          Werner syndrome RecQ like helicase
          Gene Aliases:
          RECQ3, RECQL2, RECQL3
          Chromosome Location:
          Chr.8: 31033262 - 31173761 on Build GRCh38
          UniGene ID:
          Hs.632050
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s14909

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: WRN
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000553.4 NP_000544.2 3 967
          XM_011544639.2 XP_011542941.1 3 449
          GenBank mRNA AF091214.1 - 3 410
          AY818673.1 - 2 179
          BP279291.1 - 3 360

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          More Information


          Panther Classification:

          Molecular Function -

          DNA helicase

          Gene Ontology Categories:

          Function(s) Process(es)

          telomere maintenance via recombination
          telomere maintenance
          DNA synthesis involved in DNA repair
          strand displacement
          replicative cell aging
          DNA metabolic process
          DNA replication
          base-excision repair
          double-strand break repair
          cellular response to DNA damage stimulus
          response to oxidative stress
          brain development
          aging
          cell aging
          cellular response to starvation
          response to UV-C
          multicellular organism aging
          protein sumoylation
          replication fork processing
          nucleolus to nucleoplasm transport
          DNA duplex unwinding
          regulation of growth rate
          regulation of apoptotic process
          positive regulation of hydrolase activity
          cellular response to gamma radiation
          nucleic acid phosphodiester bond hydrolysis
          regulation of signal transduction by p53 class mediator
          magnesium ion binding
          Y-form DNA binding
          bubble DNA binding
          DNA binding
          DNA helicase activity
          chromatin binding
          ATP-dependent DNA helicase activity
          helicase activity
          exonuclease activity
          protein binding
          ATP binding
          3'-5' exonuclease activity
          four-way junction helicase activity
          ATPase activity
          manganese ion binding
          protein complex binding
          protein homodimerization activity
          3'-5' DNA helicase activity
          ATP-dependent 3'-5' DNA helicase activity
          G-quadruplex DNA binding

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