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          System Message

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          LOADING ...
          See other BTK SIRNA Assays ›
          Gene Symbol:
          BTK
          Gene Name:
          Bruton tyrosine kinase
          Gene Aliases:
          AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA
          Chromosome Location:
          Chr.X: 101349447 - 101390796 on Build GRCh38
          UniGene ID:
          Hs.159494
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s2124

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: BTK
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000061.2 NP_000052.1 16 1775
          NM_001287344.1 NP_001274273.1 16 1931
          NM_001287345.1 NP_001274274.1 14 1412
          GenBank mRNA AF153364.1 - 2 127
          AF153756.1 - 2 127
          AF153757.1 - 2 127
          AF153758.1 - 2 127
          AF153759.1 - 2 127
          AF153760.1 - 2 127
          AF153761.1 - 2 127
          AF153762.1 - 2 127
          AF153764.1 - 2 123
          AJ888377.1 - 4 336
          AJ888378.1 - 4 382
          AJ888381.1 - 3 220
          AK057105.1 - 14 1366
          AK309851.1 - 16 1917
          AK314382.1 - 16 1742
          AM051275.1 - 4 337
          AM051276.1 - 5 595
          AM051280.1 - 3 229
          BC109079.1 - 16 1707 40034287
          BC109080.1 - 16 1707 40034289
          KF241986.1 - 15 1582
          X58957.1 - 16 1714

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: NM_013482, L08967, L10627, L29788, BC053392.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of cytokine production
          adaptive immune response
          regulation of B cell cytokine production
          MyD88-dependent toll-like receptor signaling pathway
          regulation of B cell apoptotic process
          transcription, DNA-templated
          protein phosphorylation
          transmembrane receptor protein tyrosine kinase signaling pathway
          I-kappaB kinase/NF-kappaB signaling
          mesoderm development
          peptidyl-tyrosine phosphorylation
          calcium-mediated signaling
          intracellular signal transduction
          peptidyl-tyrosine autophosphorylation
          Fc-epsilon receptor signaling pathway
          B cell activation
          regulation of cell proliferation
          innate immune response
          positive regulation of B cell differentiation
          cell maturation
          B cell receptor signaling pathway
          positive regulation of NF-kappaB transcription factor activity
          apoptotic signaling pathway
          protein tyrosine kinase activity
          non-membrane spanning protein tyrosine kinase activity
          receptor binding
          protein binding
          ATP binding
          phosphatidylinositol-3,4,5-trisphosphate binding
          identical protein binding
          metal ion binding

          Back To Top

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