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          System Message

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          LOADING ...
          See other HAND2 SIRNA Assays ›
          Gene Symbol:
          HAND2
          Gene Name:
          heart and neural crest derivatives expressed 2
          Gene Aliases:
          DHAND2, Hed, Thing2, bHLHa26, dHand
          Chromosome Location:
          Chr.4: 173526501 - 173530227 on Build GRCh38
          UniGene ID:
          Hs.388245
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s225137

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: HAND2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_021973.2 NP_068808.1 2 1525
          GenBank mRNA AF087940.1 - 2 491
          AK122739.1 - 3 920
          BC101406.1 - 3 566 40003700
          BC101974.1 - 3 574
          BC109383.1 - 3 339
          BF313018.1 - 2 211
          FJ226608.1 - 2 1527

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_022696, Y08138.
          This siRNA also targets the following transcripts in Mouse: NM_010402, AK035160, AJ131846.

          Panther Classification:

          Molecular Function -

          basic helix-loop-helix transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          angiogenesis
          in utero embryonic development
          heart looping
          suckling behavior
          cardiac right ventricle formation
          cardiac neural crest cell migration involved in outflow tract morphogenesis
          regulation of secondary heart field cardioblast proliferation
          apoptotic process involved in heart morphogenesis
          noradrenergic neuron differentiation
          transcription from RNA polymerase II promoter
          heart development
          adult heart development
          mesenchymal cell proliferation
          positive regulation of cardiac muscle hypertrophy
          positive regulation of gene expression
          negative regulation of gene expression
          negative regulation of cardiac muscle cell apoptotic process
          regulation of tissue remodeling
          odontogenesis of dentin-containing tooth
          embryonic digit morphogenesis
          negative regulation of DNA binding
          negative regulation of sequence-specific DNA binding transcription factor activity
          tongue development
          negative regulation of osteoblast differentiation
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          sympathetic nervous system development
          thymus development
          peripheral nervous system neuron development
          palate development
          cartilage morphogenesis
          coronary artery morphogenesis
          visceral serous pericardium development
          cardiac neural crest cell development involved in outflow tract morphogenesis
          cell proliferation involved in outflow tract morphogenesis
          positive regulation of ERK1 and ERK2 cascade
          positive regulation of p38MAPK cascade
          positive regulation of transcription regulatory region DNA binding
          positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process
          positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis
          RNA polymerase II regulatory region sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          AT DNA binding
          transcription coactivator activity
          protein binding
          transcription factor binding
          activating transcription factor binding
          protein homodimerization activity
          transcription regulatory region DNA binding
          protein heterodimerization activity
          E-box binding

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