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          System Message

          OKCancel
          LOADING ...
          See other CAV1 SIRNA Assays ›
          Gene Symbol:
          CAV1
          Gene Name:
          caveolin 1
          Gene Aliases:
          BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21
          Chromosome Location:
          Chr.7: 116524785 - 116561185 on Build GRCh38
          UniGene ID:
          Hs.74034
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s2447
          Validated

          Purification
          Size
          Availability Inventoried
          Catalog # 4390824
          Price 556.00
          Your Price
          Online offer: 529.65
          529.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: CAV1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001172895.1 NP_001166366.1 3 1209
          NM_001172896.1 NP_001166367.1 2 644
          NM_001172897.1 NP_001166368.1 3 443
          NM_001753.4 NP_001744.2 3 720
          GenBank mRNA AB209926.1 - 2 570
          AB451284.1 - 3 442
          AB451416.1 - 3 442
          AF172085.1 - 2 584
          AK290871.1 - 3 717
          AK307501.1 - 2 576
          AY762103.1 - 3 484
          BC009685.1 - 3 515
          BC082246.1 - 3 452 5441212
          BT007143.1 - 3 442
          DA477166.1 - 3 444
          EF649773.1 - 3 438
          EF649774.1 - 2 574
          Z18951.1 - 3 476

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_133651, NM_031556, XM_006236131, XM_006236130, Z46614, and others.

          Matching Taqman Gene Expression Assay:


          Hs00971716_m1

          Panther Classification:

          Molecular Function -

          scaffold/adaptor protein

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          MAPK cascade
          inactivation of MAPK activity
          angiogenesis
          vasculogenesis
          response to hypoxia
          negative regulation of endothelial cell proliferation
          positive regulation of endothelial cell proliferation
          negative regulation of cytokine-mediated signaling pathway
          response to ischemia
          regulation of the force of heart contraction by chemical signal
          triglyceride metabolic process
          calcium ion transport
          cellular calcium ion homeostasis
          regulation of smooth muscle contraction
          skeletal muscle tissue development
          response to nutrient
          lactation
          protein localization
          response to bacterium
          response to gamma radiation
          positive regulation of calcium ion transport into cytosol
          posttranscriptional regulation of gene expression
          positive regulation of gene expression
          negative regulation of muscle cell apoptotic process
          positive regulation of peptidase activity
          vesicle organization
          receptor-mediated endocytosis of virus by host cell
          regulation of fatty acid metabolic process
          lipid storage
          regulation of blood coagulation
          cholesterol transport
          negative regulation of transforming growth factor beta receptor signaling pathway
          negative regulation of epithelial cell differentiation
          mammary gland development
          organ regeneration
          positive regulation of microtubule polymerization
          T cell costimulation
          negative regulation of protein ubiquitination
          positive regulation of protein ubiquitination
          receptor internalization
          negative regulation of protein binding
          positive regulation of protein binding
          maintenance of protein location in cell
          response to progesterone
          negative regulation of peptidyl-serine phosphorylation
          positive regulation of peptidyl-serine phosphorylation
          cholesterol efflux
          nitric oxide homeostasis
          positive regulation of toll-like receptor 3 signaling pathway
          wound healing
          vasoconstriction
          response to drug
          negative regulation of tyrosine phosphorylation of Stat5 protein
          cholesterol homeostasis
          positive regulation of catalytic activity
          negative regulation of MAPK cascade
          response to estrogen
          protein localization to plasma membrane raft
          negative regulation of nitric oxide biosynthetic process
          negative regulation of neuron differentiation
          positive regulation of endocytosis
          positive regulation of vasoconstriction
          negative regulation of JAK-STAT cascade
          microtubule polymerization
          negative regulation of pinocytosis
          negative regulation of smooth muscle cell proliferation
          leukocyte migration
          regulation of nitric-oxide synthase activity
          negative regulation of nitric-oxide synthase activity
          protein homooligomerization
          response to glucocorticoid
          regulation of cytosolic calcium ion concentration
          response to calcium ion
          membrane depolarization
          regulation of peptidase activity
          calcium ion homeostasis
          mammary gland involution
          positive regulation of cell adhesion molecule production
          negative regulation of necroptotic process
          negative regulation of protein tyrosine kinase activity
          negative regulation of ERK1 and ERK2 cascade
          caveola assembly
          cellular response to mechanical stimulus
          cellular response to exogenous dsRNA
          cellular response to peptide hormone stimulus
          cellular response to hyperoxia
          cellular response to transforming growth factor beta stimulus
          caveolin-mediated endocytosis
          regulation of heart rate by cardiac conduction
          angiotensin-activated signaling pathway involved in heart process
          negative regulation of canonical Wnt signaling pathway
          positive regulation of canonical Wnt signaling pathway
          cellular senescence
          apoptotic signaling pathway
          regulation of membrane repolarization during action potential
          regulation of cardiac muscle cell action potential involved in regulation of contraction
          regulation of ventricular cardiac muscle cell action potential
          regulation of ruffle assembly
          negative regulation of peptidyl-tyrosine autophosphorylation
          negative regulation of potassium ion transmembrane transport
          regulation of cell communication by electrical coupling involved in cardiac conduction
          regulation of inward rectifier potassium channel activity
          positive regulation of ER-associated ubiquitin-dependent protein catabolic process
          protein localization to basolateral plasma membrane
          positive regulation of gap junction assembly
          beta-catenin destruction complex disassembly
          receptor internalization involved in canonical Wnt signaling pathway
          regulation of entry of bacterium into host cell
          negative regulation of anoikis
          positive regulation of extrinsic apoptotic signaling pathway
          positive regulation of intrinsic apoptotic signaling pathway
          negative regulation of cation channel activity
          RNA polymerase I transcription factor binding
          receptor binding
          patched binding
          structural molecule activity
          protein binding
          cholesterol binding
          peptidase activator activity
          enzyme binding
          protein kinase binding
          syntaxin binding
          protein binding, bridging
          protein complex scaffold
          identical protein binding
          ion channel binding
          protein heterodimerization activity
          Rac GTPase binding
          nitric-oxide synthase binding
          ATPase binding
          inward rectifier potassium channel inhibitor activity
          MDM2/MDM4 family protein binding

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          Host server : magellan-search-green-55658555d6-qfdf2:80/100.66.76.55:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline