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          System Message

          OKCancel
          LOADING ...
          See other PARK7 SIRNA Assays ›
          Gene Symbol:
          PARK7
          Gene Name:
          Parkinsonism associated deglycase
          Gene Aliases:
          DJ-1, DJ1, HEL-S-67p
          Chromosome Location:
          Chr.1: 7961654 - 7985282 on Build GRCh38
          UniGene ID:
          Hs.419640
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s502619

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PARK7
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001123377.1 NP_001116849.1 7 658
          NM_007262.4 NP_009193.2 7 716
          XM_005263424.3 XP_005263481.1 7 736
          GenBank mRNA AB073864.1 - 6 553
          AF021819.1 - 7 624
          AK091679.1 - 1 2079
          AK130886.1 - 6 551
          AK312000.1 - 7 611
          BC008188.2 - 7 637 2901102
          D61380.2 - 6 559
          EU794641.1 - 6 559

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of protein phosphorylation
          negative regulation of protein kinase activity
          proteolysis
          protein deglycosylation
          autophagy
          inflammatory response
          mitochondrion organization
          Ras protein signal transduction
          single fertilization
          adult locomotory behavior
          detoxification of copper ion
          positive regulation of gene expression
          negative regulation of gene expression
          enzyme active site formation via L-cysteine sulfinic acid
          methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
          lactate biosynthetic process
          protein repair
          negative regulation of protein ubiquitination
          negative regulation of protein binding
          activation of protein kinase B activity
          negative regulation of proteasomal ubiquitin-dependent protein catabolic process
          positive regulation of interleukin-8 production
          positive regulation of peptidyl-serine phosphorylation
          negative regulation of protein sumoylation
          cellular response to oxidative stress
          cellular response to glyoxal
          response to drug
          hydrogen peroxide metabolic process
          negative regulation of apoptotic process
          regulation of neuron apoptotic process
          negative regulation of neuron apoptotic process
          regulation of TRAIL receptor biosynthetic process
          positive regulation of transcription from RNA polymerase II promoter
          glycolate biosynthetic process
          negative regulation of protein export from nucleus
          regulation of inflammatory response
          detoxification of mercury ion
          protein stabilization
          positive regulation of sequence-specific DNA binding transcription factor activity
          negative regulation of ubiquitin-protein transferase activity
          dopamine uptake involved in synaptic transmission
          regulation of mitochondrial membrane potential
          positive regulation of protein kinase B signaling
          membrane depolarization
          membrane hyperpolarization
          negative regulation of cell death
          regulation of androgen receptor signaling pathway
          cellular response to hydrogen peroxide
          positive regulation of protein homodimerization activity
          cell-cell adhesion
          cellular oxidant detoxification
          positive regulation of protein localization to nucleus
          negative regulation of neuron death
          positive regulation of superoxide dismutase activity
          negative regulation of protein acetylation
          positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          regulation of fibril organization
          positive regulation of mitochondrial electron transport, NADH to ubiquinone
          negative regulation of death-inducing signaling complex assembly
          negative regulation of protein K48-linked deubiquitination
          negative regulation of TRAIL-activated apoptotic signaling pathway
          positive regulation of pyrroline-5-carboxylate reductase activity
          positive regulation of tyrosine 3-monooxygenase activity
          positive regulation of dopamine biosynthetic process
          glyoxal catabolic process
          positive regulation of L-dopa biosynthetic process
          positive regulation of L-dopa decarboxylase activity
          negative regulation of oxidative stress-induced cell death
          negative regulation of hydrogen peroxide-induced cell death
          negative regulation of hydrogen peroxide-induced neuron death
          negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
          negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
          positive regulation of reactive oxygen species biosynthetic process
          positive regulation of mitophagy
          negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
          negative regulation of ubiquitin-specific protease activity
          positive regulation of oxidative phosphorylation uncoupler activity
          positive regulation of transcription regulatory region DNA binding
          positive regulation of androgen receptor activity
          negative regulation of extrinsic apoptotic signaling pathway
          negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
          core promoter binding
          double-stranded DNA binding
          single-stranded DNA binding
          transcription coactivator activity
          mRNA binding
          receptor binding
          copper ion binding
          protein binding
          transcription factor binding
          peptidase activity
          superoxide dismutase copper chaperone activity
          oxidoreductase activity, acting on peroxide as acceptor
          glyoxalase III activity
          enzyme binding
          kinase binding
          cytokine binding
          tyrosine 3-monooxygenase activator activity
          L-dopa decarboxylase activator activity
          identical protein binding
          protein homodimerization activity
          small protein activating enzyme binding
          ubiquitin-like protein conjugating enzyme binding
          mercury ion binding
          androgen receptor binding
          peroxiredoxin activity
          repressing transcription factor binding
          scaffold protein binding
          cadherin binding involved in cell-cell adhesion
          cupric ion binding
          cuprous ion binding
          ubiquitin-specific protease binding
          glyoxalase (glycolic acid-forming) activity

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