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          LOADING ...
          See other ERCC2 SIRNA Assays ›
          Gene Symbol:
          ERCC2
          Gene Name:
          ERCC excision repair 2, TFIIH core complex helicase subunit
          Gene Aliases:
          COFS2, EM9, TFIIH, TTD, TTD1, XPD
          Chromosome Location:
          Chr.19: 45349837 - 45370647 on Build GRCh38
          UniGene ID:
          Hs.487294
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s534582

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ERCC2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000400.3 NP_000391.1 17 1674
          XM_011526611.2 XP_011524913.1 16 1656
          XM_017026467.1 XP_016881956.1 16 1570
          GenBank mRNA AK092872.1 - 4 1715
          AK130849.1 - 6 798
          BC108255.1 - 17 1637 6044425
          BC110522.1 - 15 1421 40034047
          BC110523.1 - 17 1655 40034048
          X52221.1 - 16 2308

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          More Information


          Panther Classification:

          Molecular Function -

          DNA helicase

          Gene Ontology Categories:

          Function(s) Process(es)

          nucleotide-excision repair, DNA duplex unwinding
          response to hypoxia
          in utero embryonic development
          transcription-coupled nucleotide-excision repair
          nucleotide-excision repair
          nucleotide-excision repair, preincision complex stabilization
          nucleotide-excision repair, preincision complex assembly
          nucleotide-excision repair, DNA incision, 3'-to lesion
          nucleotide-excision repair, DNA incision, 5'-to lesion
          transcription initiation from RNA polymerase I promoter
          transcription elongation from RNA polymerase I promoter
          termination of RNA polymerase I transcription
          transcription from RNA polymerase II promoter
          transcription initiation from RNA polymerase II promoter
          transcription elongation from RNA polymerase II promoter
          7-methylguanosine mRNA capping
          protein phosphorylation
          apoptotic process
          response to oxidative stress
          chromosome segregation
          aging
          cell proliferation
          UV protection
          post-embryonic development
          viral process
          spinal cord development
          extracellular matrix organization
          bone mineralization
          central nervous system myelin formation
          nucleotide-excision repair, DNA incision
          multicellular organism growth
          hair cell differentiation
          embryonic cleavage
          erythrocyte maturation
          positive regulation of DNA binding
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          hair follicle maturation
          hematopoietic stem cell differentiation
          global genome nucleotide-excision repair
          regulation of mitotic cell cycle phase transition
          DNA binding
          ATP-dependent DNA helicase activity
          protein kinase activity
          protein binding
          ATP binding
          protein C-terminus binding
          DNA-dependent ATPase activity
          RNA polymerase II carboxy-terminal domain kinase activity
          5'-3' DNA helicase activity
          metal ion binding
          protein N-terminus binding
          4 iron, 4 sulfur cluster binding

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