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          System Message

          OKCancel
          LOADING ...
          See other HMGB1 SIRNA Assays ›
          Gene Symbol:
          HMGB1
          Gene Name:
          high mobility group box 1
          Gene Aliases:
          HMG-1, HMG1, HMG3, SBP-1
          Chromosome Location:
          Chr.13: 30457916 - 30617597 on Build GRCh38
          UniGene ID:
          Hs.434102
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s6645

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: HMGB1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001313892.1 NP_001300821.1 5 1586
          NM_001313893.1 NP_001300822.1 5 2346
          NM_002128.5 NP_002119.1 5 1589
          GenBank mRNA AK057120.1 - 5 1451
          AK122825.1 - 5 2347
          AL110194.1 - 1 186
          BC030981.1 - 5 1499 4041682
          BC141844.1 - 5 1480 8860319
          CR749614.1 - 5 1577

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          eye development
          myeloid dendritic cell activation
          endothelial cell proliferation
          activation of innate immune response
          plasmacytoid dendritic cell activation
          macrophage activation involved in immune response
          dendritic cell chemotaxis
          inflammatory response to antigenic stimulus
          regulation of tolerance induction
          regulation of T cell mediated immune response to tumor cell
          DNA topological change
          base-excision repair
          apoptotic DNA fragmentation
          DNA recombination
          regulation of transcription from RNA polymerase II promoter
          autophagy
          inflammatory response
          positive regulation of cytosolic calcium ion concentration
          regulation of autophagy
          negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
          lung development
          neuron projection development
          chromatin assembly
          regulation of restriction endodeoxyribonuclease activity
          activation of protein kinase activity
          DNA geometric change
          positive regulation of mismatch repair
          negative regulation of interferon-gamma production
          positive regulation of interferon-alpha production
          positive regulation of interferon-beta production
          positive regulation of interleukin-10 production
          positive regulation of interleukin-12 production
          positive regulation of tumor necrosis factor production
          V(D)J recombination
          positive regulation of toll-like receptor 2 signaling pathway
          positive regulation of toll-like receptor 4 signaling pathway
          positive regulation of toll-like receptor 9 signaling pathway
          T-helper 1 cell activation
          endothelial cell chemotaxis
          positive regulation of activated T cell proliferation
          positive regulation of apoptotic process
          apoptotic cell clearance
          positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
          negative regulation of CD4-positive, alpha-beta T cell differentiation
          positive regulation of DNA binding
          positive regulation of MAPK cascade
          negative regulation of blood vessel endothelial cell migration
          T-helper 1 cell differentiation
          innate immune response
          positive regulation of myeloid cell differentiation
          positive regulation of glycogen catabolic process
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JNK cascade
          positive regulation of interleukin-1 secretion
          positive regulation of interleukin-1 beta secretion
          positive chemotaxis
          DNA ligation involved in DNA repair
          positive regulation of DNA ligation
          response to glucocorticoid
          positive regulation of ERK1 and ERK2 cascade
          positive regulation of monocyte chemotaxis
          positive regulation of wound healing
          neutrophil clearance
          positive regulation of NIK/NF-kappaB signaling
          positive regulation of sprouting angiogenesis
          tumor necrosis factor secretion
          negative regulation of apoptotic cell clearance
          positive regulation of interleukin-6 secretion
          regulation of nucleotide-excision repair
          positive regulation of dendritic cell differentiation
          four-way junction DNA binding
          bubble DNA binding
          lipopolysaccharide binding
          phosphatidylserine binding
          damaged DNA binding
          double-stranded DNA binding
          single-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          double-stranded RNA binding
          single-stranded RNA binding
          cytokine activity
          protein binding
          transcription factor binding
          DNA binding, bending
          calcium-dependent protein kinase regulator activity
          lyase activity
          C-X-C chemokine binding
          protein kinase activator activity
          chemoattractant activity
          poly(A) RNA binding
          RAGE receptor binding
          DNA polymerase binding
          repressing transcription factor binding
          supercoiled DNA binding

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          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
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