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LOADING
See other IRS1 SIRNA Assays ›
Gene Symbol:
IRS1
Gene Name:
insulin receptor substrate 1
Gene Aliases:
HIRS-1
Chromosome Location:
Chr.2: 226731317 - 226798790 on Build GRCh38
UniGene ID:
Hs.471508
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID
s7520
Purification
Standard
HPLC
HPLC-IVR
Size
1 nmol
5 nmol
InVivo | 5 nmol
20 nmol
20 nmol
40 nmol
40 nmol
250 nmol
250 nmol
InVivo | 250 nmol
InVivo | 250 nmol
1 umol
1 umol
InVivo | 1 umol
InVivo | 1 umol
10 umol
10 umol
1 nmol
5 nmol
InVivo | 5 nmol
20 nmol
20 nmol
40 nmol
40 nmol
250 nmol
250 nmol
InVivo | 250 nmol
InVivo | 250 nmol
1 umol
1 umol
InVivo | 1 umol
InVivo | 1 umol
10 umol
10 umol
1 nmol
5 nmol
InVivo | 5 nmol
20 nmol
20 nmol
40 nmol
40 nmol
250 nmol
250 nmol
InVivo | 250 nmol
InVivo | 250 nmol
1 umol
1 umol
InVivo | 1 umol
InVivo | 1 umol
10 umol
10 umol
Availability
Inventoried
Catalog #
4392420
Price
Your Price
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Genomic Map
siRNA Details
More Information
Genomic Map
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siRNA Details
Gene Symbol: IRS1
Interrogated Sequence
Translated Protein
Targeted Exon(s)
siRNA Location
IMAGE Clone ID
RefSeq
NM_005544.2
NP_005535.1
1
580
GenBank mRNA
BC053895.1
-
1
580
6144252
S62539.1
-
1
1548
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More Information
Other Species Targeted
This siRNA also targets the following transcripts in Mouse: NM_010570, AK142242, AK045317, X69722, L24563.
Gene Ontology Categories:
Function(s)
Process(es)
MAPK cascade
signal transduction
positive regulation of cell proliferation
insulin receptor signaling pathway
positive regulation of glucose metabolic process
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of fatty acid beta-oxidation
response to insulin
cellular response to insulin stimulus
phosphatidylinositol-3-phosphate biosynthetic process
glucose homeostasis
response to peptide hormone
positive regulation of GTPase activity
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of glycogen biosynthetic process
positive regulation of glucose import
negative regulation of insulin receptor signaling pathway
positive regulation of insulin receptor signaling pathway
negative regulation of insulin secretion
phosphatidylinositol phosphorylation
insulin-like growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
positive regulation of glucose import in response to insulin stimulus
signal transducer activity
transmembrane receptor protein tyrosine kinase adaptor activity
protein kinase C binding
Ras guanyl-nucleotide exchange factor activity
insulin receptor binding
insulin-like growth factor receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
SH2 domain binding
phosphatidylinositol 3-kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
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