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          System Message

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          LOADING ...
          See other ACVRL1 SIRNA Assays ›
          Gene Symbol:
          ACVRL1
          Gene Name:
          activin A receptor like type 1
          Gene Aliases:
          ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
          Chromosome Location:
          Chr.12: 51906913 - 51923361 on Build GRCh38
          UniGene ID:
          Hs.591026
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s986

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ACVRL1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000020.2 NP_000011.2 3 536
          NM_001077401.1 NP_001070869.1 2 399
          XM_005269235.2 XP_005269292.1 4 538
          XM_011539008.1 XP_011537310.1 2 394
          GenBank mRNA BC042637.1 - 2 285 5179243
          DN999570.1 - 3 544
          HM161905.1 - 4 543
          HM161906.1 - 4 503
          KU177888.1 - 2 253
          KU177889.1 - 2 253
          L17075.1 - 2 344
          Z22533.1 - 3 535

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          More Information


          Panther Classification:

          Molecular Function -

          serine/threonine protein kinase receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          angiogenesis
          in utero embryonic development
          regulation of endothelial cell proliferation
          negative regulation of endothelial cell proliferation
          positive regulation of endothelial cell proliferation
          lymphangiogenesis
          blood vessel maturation
          blood vessel remodeling
          blood vessel endothelial cell proliferation involved in sprouting angiogenesis
          endocardial cushion morphogenesis
          regulation of DNA replication
          regulation of transcription, DNA-templated
          protein phosphorylation
          negative regulation of cell adhesion
          signal transduction
          transforming growth factor beta receptor signaling pathway
          blood circulation
          regulation of blood pressure
          negative regulation of cell proliferation
          negative regulation of endothelial cell migration
          negative regulation of gene expression
          positive regulation of pathway-restricted SMAD protein phosphorylation
          signal transduction by protein phosphorylation
          negative regulation of cell growth
          negative regulation of cell migration
          BMP signaling pathway
          positive regulation of BMP signaling pathway
          positive regulation of chondrocyte differentiation
          activin receptor signaling pathway
          wound healing, spreading of epidermal cells
          dorsal aorta morphogenesis
          regulation of blood vessel endothelial cell migration
          negative regulation of blood vessel endothelial cell migration
          negative regulation of endothelial cell differentiation
          positive regulation of endothelial cell differentiation
          positive regulation of angiogenesis
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          protein heterooligomerization
          negative regulation of focal adhesion assembly
          lymphatic endothelial cell differentiation
          artery development
          venous blood vessel development
          endothelial tube morphogenesis
          retina vasculature development in camera-type eye
          cellular response to transforming growth factor beta stimulus
          cellular response to BMP stimulus
          endocardial cushion to mesenchymal transition
          negative regulation of DNA biosynthetic process
          protein serine/threonine kinase activity
          transmembrane receptor protein serine/threonine kinase activity
          receptor signaling protein serine/threonine kinase activity
          transforming growth factor beta-activated receptor activity
          transforming growth factor beta receptor activity, type I
          protein binding
          ATP binding
          activin receptor activity, type I
          protein kinase binding
          SMAD binding
          metal ion binding
          activin binding
          transforming growth factor beta binding
          BMP receptor activity

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