Advanced CO₂ Incubation

Embark on the remarkable

Advanced incubation solutions enable the creation of novel cultures and therapies. Our most innovative CO₂ Incubators offer designs that support groundbreaking science including: automated technologies, GMP and cleanroom requirements, and scale-up processes. View the comparison chart below to explore the features of all of our advanced CO₂ incubators.

Designed for integration into automated laboratories

Thermo Scientific Vios iDx AD 255 CO₂ Incubators are designed for integration into automated laboratories that leverage a modular design to scale. The VIOS family of incubators are known for optimal cell growth conditions and minimal contamination risk. With the added innovation of a patent-pending automated door control, these leading incubators now bring their excellent recovery and uniformity to emerging automated cell therapy production processes 24/7, 365.

Many industry experts agree that human handling and complex processes limit broader application of cutting-edge cell therapies to treat cancer, autoimmunity, and orphan diseases. As automation is incorporated across the sector, these treatments can be produced in a more cost effective way. Several companies are developing advanced robotics to help meet these goals and Heracell VIOS 250i AxD CO₂ Incubators are a natural fit. Various therapies are researched and developed in these incubators due to their excellent culturing conditions that help ensure important cellular critical quality attributes.

Vios iDx AD 255 CO₂ Incubator

Automated operation of incubator door
Simplified door design, well suited for robotic interface
Automatic stop if an obstruction is encountered
Patented Thermo Scientific THRIVE active airflow technology for homogenous growth conditions
Remote control and foot pedal configurations for assisted door opening available
Integration-ready for automated production settings that leverage a modular design to scale
Built with all benefits of Vios iDx 255 CO₂ Incubators with additional configurations available

Cleanroom compatible CO₂ incubators

Thermo Scientific Vios iDx CR CO₂ Incubators are third-party certified cleanroom compatible and suitable for ISO Class 5 and Good Manufacturing Practices (GMP) grade A/B environments. They feature an active particle control system and demonstrated compatibility with commonly used cleanroom cleaning methods, making it the exceptional fit for your cleanroom suite or GMP production environment.

Download our ebook Five Reasons to choose a cleanroom CO₂ incubator that is certified compatible for an in-depth look at the advantages of using a CO₂ incubator with cleanroom certification.

Features of all cleanroom compatible incubators

Cleanroom certified

Through rigorous testing, the Vios iDx CR CO₂ incubators have successfully achieved ISO class 5 compatibility for the considered particle sizes in both standard operating and sterilization modes.

Robust and easy to clean

Brushed 304 stainless steel exterior is compatible with STERIS dry non-condensing VHP and 3% manual wipe hydrogen peroxide cleaning methods typically used in cleanroom environments.
Sealed exterior casing includes silicone sealed electronics and welded door to contain any particulate risk.
IP54 rated componentry protects electronics from dust and is resistant to water spray from any direction.

Documentation package including:

Regulatory certificates
Declaration of Conformity (CE) with EU law, CSA and QMS Certificates
Recommended protocols
User-replaceable parts and consumables lists
Product-specific factory documentation and specification
Certificates of conformance, calibration, and technical specifications
3rd party certificate of compatibility with ISO Class 5 and GMP Grade A/B cleanroom environments

Advanced CO2 Incubators Comparison

Vios iDx CR 165 CO₂ Incubator – CTS Series	Vios iDx CR 255 CO₂ Incubator – CTS Series	Forma Steri-Cult CO₂ Incubator – CTS Series	Large-Capacity Reach-In CO₂Incubator	Vios iDx AD 255 CO₂ Incubator
Specialized features
Certified cleanroom compatible, ISO Class 5, GMP Grade A/B environments, FAT documentation package included		Largest capacity stackable option, FAT documentation package	Largest capacity CO₂ incubator option	Automated door for continuous hands-free operation
Individual chamber volume
165 L	255 L	232 L or 323 L	821 L	255L
Chamber material
Brushed stainless steel exterior casing with IP54 compliance		Powder-coated cold-rolled steel		Powder-coated cold-rolled steel or optional brushed stainless steel
Sensors
IR180SI	IR180Si	IR180Si	TC180	IR180Si
Sterilization
Steri-Run High-Temperature Sterilization Cycle		140 ° Sterilization Cycle	--	Steri-Run High-Temperature Sterilization Cycle
Oxygen control
1 – 21 %, 5 – 90 % optional		--	--	1 – 21 %
Relative humidity
>93 % at 37 °C		95 %, Controllable	<80 %, High <90 %	>93 % at 37 °C
Filtration
Interior HEPA filter for ISO Class 5 chamber conditions, exterior HEPA filter to particulate control		Interior HEPA filter for ISO Class 5 chamber conditions		Interior HEPA filter for ISO Class 5 chamber conditions
Data and connectivity
USB, 4-20mA, Thermo Scientific Connect Edge, and OPC-UA Gateway for 21 CFR Part 11-compliance and GMP needs		Optional 4-20mA	Optional 4-20mA	USB, 4-20mA, Thermo Scientific Connect Edge, and OPC-UA Gateway for 21 CFR Part 11-compliance and GMP needs
Stacking options
Stack two incubators by combining the desired two incubators with: Cleanroom 165 L low-profile roller base Cleanroom 165 L stacking adapter	Stack two incubators by combining the desired two incubators with: Cleanroom 255 L low-profile roller base Cleanroom 255 L stacking adapter	Speak to a specialist about your requirements.	--	Speak to a specialist about your requirements.

View all CO2 incubator specifications with the CO2 incubator selection guide

Scale-up with CultiMaxx Shelving Systems

As you scale out your cell therapy manufacturing, the incubator you have come to trust can now adjust with you. To match your changing needs, our special shelving system options offer additional capacity and/or improved access for specialized cell culture vessels such as Wilson Wolf G-Rex® 500M-CS bioreactors or Thermo Scientific Nunc Cell Factory systems.

These dedicated shelving systems are available as separate accessories. Each offers several advantages as you enter the cell expansion stage using larger cell culture vessels.

Stainless steel reinforced shelves

Available as accessory

Easy installation and retrofittable

View options for Vios iDx CR, Steri-Cult, and Large Capacity Reach-In CO₂ incubators

CultiMaxx Shelving for G-Rex Bioreactors, Nunc Cell Factory Systems and 1 L Culture Bags in Vios iDx CO2 Incubators.

Shop by vessel type

Shelving System	Vessel Type	Advantages	Action
CultiMaxx shelving system for 1 L cell culture bags		Up to 2.5x more culture bag capacity per incubator and increased exposure to promote better gas exchange	Buy now ›
CultiMaxx shelving system for 10x Nunc Cell Factory 4-layer systems		Accommodates 1 more Cell Factory system, easy access, improved clearance for air filters	Buy now ›
CultiMaxx shelving system for 6x Nunc Cell Factory 10- or 13- systems		Easy access, better clearance for air filter	Buy now ›
CultiMaxx shelving system for up to 10x G-Rex® 500M-CS (or up to 45x 100M-CS or 123x 10M-CS)		150% more capacity compared to standard shelving	Buy now ›