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Pre-packed chromatography columns for bioprocess applications

Chromatography columns are critical to achieving successful separation of any biomolecule in downstream applications. Our pre-packed chromatography columns are designed to save time and money when used in your biotherapeutic purification workflow. We offer a variety of column sizes and formats, packed with Thermo Scientific chromatography resins. Our columns range in size from small volume RoboColumns, such as GoPure and MiniChrom™ columns used for process development, to bench scale.

 

No matter what your application is, we have a packed column ready when you are. Our pre-packed columns can help increase your productivity by:

  • Offering a quick and easy set-up
  • Allowing for increased process flexibility
  • Helping create efficiencies so there is more time for more test runs
  • Reducing labor time related to column packing and cleaning

Pre-packed chromatography columns for multiple applications

Our pre-packed columns come in a variety of formats, suitable for high throughput screening, process development, bench-scale screening, and small-scale preparative chromatography.

Column type

RoboColumn™

GoPure small-scale prepacked column

MiniChrom column

 

Prepacked column

Application

  • High throughput screening
  • Process development
  • Process development
  • Bench-scale screening
  • Preparative chromatography
  • Process development
  • Bench-scale screening
  • Preparative chromatography
  • Preparative chromatography

Volume

50 µL

200 µL

600 µL

1 mL

5 mL

1 mL

5 mL

1 mL

5 mL

Diameter

0.5 cm

0.5 cm

0.5 cm

0.5 cm

0.8 cm

0.8 cm

0.8 cm

0.7 cm

1.4 cm

Bed height

0.25 cm

1 cm

3 cm

5 cm

10 cm

2 cm

10 cm

2.5 cm

3.25 cm

High throughput screening (Process development)

RoboColumns are small chromatography columns that are provided in 8-column strips. These columns are useful for fully automated and parallel chromatographic separations using a robotic liquid handling platform and are available in 50 µL, 200 µL, and 600 µL volumes.

 

Bench-scale process development screening

The GoPure and MiniChrom columns are designed for bench-scale resin screening, process development, and sample preparation. The 1 mL columns can be used for quick screenings of application feasibility and lab scale purification on a convenient and easy-to-use pre-packed column. The 10 cm bed height of the 5 mL columns allows initial process development on a bench scale.

 

Preparative chromatography

For your small-scale preparative chromatography needs, we have pre-packed our affinity resins into columns which can be used for simple and efficient protein purification in small volumes.


Find your column by resin type

Affinity

The CaptureSelect affinity chromatography technology offers a unique affinity purification solution based on single domain [VHH] antibody fragments. The affinity resins provide high target purity in a single step, independent of feedstock.

 

The affinity ligands are developed to meet all predefined requirements such as high specificity to the target molecule, mild elution during the purification process and high stability of the final resin. Manufacturing in an animal free production process allows for use in commercial purification processes

Product

RoboColumn

(50 µL/200 µL/600 µL)

GoPure 0.2 or 1 mL / MiniChrom 1 mL

GoPure 5 mL/ MiniChrom
5 mL

pre-packed 1 mL

pre-packed 5 mL

Viral vectors

AAVX

A37794

(200 µL)

A37795

(600 µL)

A36652

A36651

 

 

AAV8

 

A36648

A36647

 

 

AAV9

 

A36650

A36649

 

 

Product

RoboColumn

(50 µL/200 µL/600 µL)

GoPure 0.2 or 1 mL / MiniChrom 1 mL

GoPure 5 mL/ MiniChrom
5 mL

pre-packed 1 mL

pre-packed 5 mL

Proteins

C-tagXL

 

5943072001

5943072005

494307201

494307205

Product

RoboColumn

(50 µL/200 µL/600 µL)

GoPure 0.2 or 1 mL / MiniChrom 1 mL

GoPure 5 mL/ MiniChrom
5 mL

pre-packed 1 mL

pre-packed 5 mL

Antibodies

           

 

 

 

 

 

 

FcXP

5943712200
(200 µL)

5943712001

5943712005

494371201

494371205

CH1-XL

5943462200

(200 µL)

5943462001

5943462005

494346201

494346205

KappaXP

5943212200
(200 µL)

 

5943212005

494321201

494321205

LambdaXP

 

594375001

594375005

 

 

MabCaptureC

(Protein A)

5943662200

(200 µL)
5943662600

(600 µL)

5943662001

5943662005

 

 

Product

RoboColumn

(50 µL/200 µL/600 µL)

GoPure 0.2 or 1 mL / MiniChrom 1 mL

GoPure 5 mL/ MiniChrom
5 mL

pre-packed 1 mL

pre-packed 5 mL

mRNA

POROS Oligo (dT)25

A48349
(200 µL)

A48350
(600 µL)

A48351
(0.2 mL)

A48352
(1 mL)

A48607

 

 

Ion exchange

POROS Ion Exchange Resins are designed for high-dynamic binding capacity over a range of pH and conductivity conditions, thereby increasing process development flexibility and manufacturing throughput.

 

POROS HS and XS resins are strong cation exchange resins based on a sulfopropyl functionalization, designed for the purification of more basic proteins and biomolecules. They are especially well suited for the separation of process impurities and aggregates.

Resin type

Product

RoboColumn 200 µL

RoboColumn 600 µL

GoPure 1 mL

GoPure 5 mL

Anion

HQ 50

A30717

A30718

4481315

A36639

XQ

A30719

A30720

A25812

A36640

PI 50

A30721

A30722

4481318

A36641

D 50

A30723

A30724

4481319

A36642

Resin type

Product

RoboColumn 200 µL

RoboColumn 600 µL

GoPure 1 mL

GoPure 5 mL

Cation

HS 50

A30713

A30714

4481316

A36637

XS

A30715

A30716

4481317

A36638

Hydrophobic interaction

POROS HIC resins are available in a differentiating range of hydrophobicity, suitable for bind/elute and flow-through applications. The resins can be utilized at lower salt concentrations for the purification of a wide variety of biomolecules including therapeutic proteins, antibody fragments, antibody drug conjugates (ADCs), and other large molecules.  

 

Resin type

Product

RoboColumn 200 µL

RoboColumn 600 µL

GoPure 1 mL

GoPure 5 mL

HIC

Ethyl

A34810

A34812

A34983

A36653

Benzyl

A34813

A34814

A34984

A36654

Benzyl Ultra

A34815

A34816

A34985

A36655

Chromatography Learning Lab

Check out the new Chromatography Learning Lab from Thermo Fisher Scientific, providing a robust range of webinars, articles, eBooks, infographics, and other digital resources to help you optimize the use of our purification products in your process.

 


Additional resources

Enhance your bioprocessing knowledge with educational content to help you understand issues, solve problems, and make solid decisions.

Deep dive into a targeted collection of scientific application notes, case studies, posters, white papers and more for bioprocessing.

Learn, evaluate, connect.


 

 

 

Connect with a Bioprocessing representative or request more info.

 

 

Thermo Fisher Bioprocessing Portfolio

Upstream bioprocessing

Develop and scale biomanufacturing processes efficiently with trusted technologies and full-service support.

 

Downstream bioprocessing

Streamline downstream biomanufacturing and improve product quality with innovative technologies and outsourcing services to drive efficiency.

Assurance of supply

We strive to support industry growth by investing in capacity and quality systems for a reliable supply of critical materials.