Enriched cells for less noise in your final result

Invitrogen™ MagniSort™ technology is designed to offer column-free magnetic separation platform for cell enrichment that is simpler, faster, and offers significant cost-savings compared to column-based separation methods. When absolute purity is not necessary, as is often the case with in vitro stimulation of T cells or the derivation of macrophages from peripheral blood monocytes, magnetic cell separation can deliver highly enriched cells without exposure to harsh separation protocols like flow cytometric sorting, or chemical gradients. 

The MagniSort Assay incorporates an easy-to-follow protocol for isolation of both positive and negative fractions.

 

Advantages of MagniSort kits over column-based kits
  • Help save time and money
  • Treat cells gently with no passage through a column
  • Eliminate cost and waste of disposable columns
  • Process 2 x 109 cells per kit (two times that of leading competitor)
Enrichment kits

Undesired cells in the sample are bound by a specific cocktail of biotinylated antibodies (included in the kits). Streptavidin-coated magnetic beads (included in the kit) are then added to the sample. When the sample is placed in a magnetic field, the undesired cells are sequestered, leaving the desired cells untouched and free in solution. 

The MagniSort Magnet is designed to be used with 12 x 75 mm round-bottom polystyrene tubes and the kits mentioned below.

Depletion kits

Using a biotinylated antibody and streptavidin-coated magnetic beads, these kits are designed to sequester specific cellular subsets. The unbound cells can then be decanted, and the sample will be depleted of the subset.

The MagniSort Magnet is designed to be used with 12 x 75 mm round-bottom polystyrene tubes and the kits mentioned below.

MagniSort beads for use with your own antibody

MagniSort Streptavidin Positive Selection Beads may be used with a biotinylated antibody of your choice for either positive selection (desired cells are bound to the bead) or negative selection/depletion (undesired cells are bound to the bead). For negative selection/depletion using a cocktail of antibodies (rather than a single antibody), choose MagniSort Negative Selection Beads.

The MagniSort Magnet is designed to be used with 12 x 75 mm round-bottom polystyrene tubes and the Positive and Negative Selection Beads above.

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