This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
activation induced deaminase; Activation-induced cytidine deaminase; AICDA; AID; ARP2; CDA2; Cytidine aminohydrolase; epididymis secretory protein Li 284; HIGM2; integrated into Burkitt's lymphoma cell line Ramos; Single-stranded DNA cytosine deaminase
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