Anti-E-cadherin Antibodies

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E-cadherin Antibodies

Antibodies that detect E-cadherin can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target E-cadherin in Human, Mouse, Non-human primate, Rat and Canine samples. Our E-cadherin monoclonal, polyclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit, Mouse, Rat and Goat. These antibodies have been verified by IP-MS, Relative expression, Cell treatment and Independent antibody to confirm specificity to E-cadherin. Find the E-cadherin antibody that fits your needs. Choose from 1 of 128 E-cadherin antibodies, which have been validated in experiments with 1593 publications and ... View more Antibodies that detect E-cadherin can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target E-cadherin in Human, Mouse, Non-human primate, Rat and Canine samples. Our E-cadherin monoclonal, polyclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit, Mouse, Rat and Goat. These antibodies have been verified by IP-MS, Relative expression, Cell treatment and Independent antibody to confirm specificity to E-cadherin. Find the E-cadherin antibody that fits your needs. Choose from 1 of 128 E-cadherin antibodies, which have been validated in experiments with 1593 publications and 828 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.

Synonyms

AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-Cadherin phospho; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; phospho cadherin 1; phospho E-Cadherin; phospho LCAM; phospho S838; phospho UVO; S840; S840 E-Cadherin; Ser840; Ser840 E-Cadherin; Um; UVO; Uvomorulin