Benefit from uniquely accurate and precise quantitation, deep proteome coverage and data completeness. The premier quantitative Thermo Scientific Velocity LFQ data-independent acquisition (DIA) proteomics platform delivers high-confidence characterization of the differences between biological systems.

Now you can afford your first choice.The Velocity LFQ DIA platform includes the award-winning Thermo Scientific Orbitrap Exploris series of mass spectrometers, Thermo Scientific Vanquish Neo UHPLC system, custom Thermo Scientific μPAC Neo HPLC columns, Thermo Scientific EASY-Spray nano source, and the software you need to analyze your data.

Discover how Velocity LFQ DIA addresses clinical proteomics and large-scale populational studies

High-throughput high-resolution DIA workflow for accurate label-free quantitation

High-throughput high-resolution data-independent acquisition workflow for accurate label-free quantitation
Velocity DIA workflow for label-free quantitation of proteome mixtures. Configuration highlights quantitative performance at high sample throughput, delivering robust and reproducible results. This workflow is a perfect fit for large-scale clinical and biomarker discovery studies.
Graphical schematic of DIA workflow
The Velocity LFQ DIA platform is a premier quantitative proteomics system that uniquely delivers robust quantitative accuracy and precision, in combination with high proteome coverage and data completeness, for high-confidence, high-throughput characterization of large sample cohorts, for investigators in quantitative proteomics, translational research, biomarker discovery, and biopharma research labs, who need to characterize the differences between biological systems using precise quantitative measurements for hypothesis testing.

High confidence with deep proteome coverage and data completeness

  • Direct DIA provides >99% data completeness
  • Thermo Scientific Proteome Discoverer 3.1 software with CHIMERYS™ intelligent search algorithm by MSAID for deeper proteome profiling for screening approaches

High throughput for large sample cohorts reduces time to biological insight

  • Provides statistical significance
  • Vanquish Neo UHPLC system and µPAC Neo columns provide high efficiency separations


"By performing high-throughput analyses on projects involving hundreds of clinical research samples, the DIA mode on the Orbitrap Exploris 480 mass spectrometer has enabled us to achieve deep and quantifiable proteome coverage (for Research Use Only) and reproducibility, maximizing the possibilities for biomarker discovery and validation."

Florence Roux-Dalvai, Proteomics project manager, ADLab, Research Center of CHU de Québec – Université Laval Hospital - Canada

1000 Orbitrap DIA Publications

Over one thousand peer-reviewed publications with Orbitrap mass spectrometers, covering a very broad range of proteomic applications, including for example analysis of SARS-CoV-2 host proteins, protein functions, noninvasive proteomics biomarkers, drugs, protein shapes and proteogenomic subtypes of acute myeloid leukemia. A subset of the 1000 publications are highlighted below.

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