KingFisher Instruments
Thermo Scientific KingFisher instruments use magnetic bead technology to automate nucleic acid and protein purification. Our automated solution reduces user variability and hands-on time for a variety of applications and throughput levels, delivering a versatile system that can adapt to your changing research needs while maintaining consistent results.
Find the right KingFisher instrument for you
| KingFisher Duo Prime | KingFisher Flex | KingFisher Presto | |
|---|---|---|---|
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| Size | Compact Benchtop | Benchtop | Integrate with liquid handler handler |
| Throughput | Low–Med throughput 6/12/24 samples per run/load |
Med–High throughput 24/96 samples per run |
High throughput 96 samples per run |
| Volume range | 30-5000 µl | 20-5000 µl | 50-5000 µl |
| Request demo Learn more |
Request demo Learn more |
Request demo Learn more |
|
| Compare all instruments | |||
How KingFisher technology works
The Thermo Scientific KingFisher Purification System utilizes permanent magnetic rods and disposable tip combs. When the magnetic rod—sheathed inside the tip comb—is lowered into the solution, magnetic beads collect at the bottom of the tip comb. The tip comb can then be positioned in a different row or plate, and the beads are then released by moving the magnetic rods out of the tip comb. The tip comb also facilitates the mixing of reagents with the beads by moving up and down.
Diagram details the KingFisher
workflow
Watch the video for a detail view of the workflow
Find the right KingFisher instrument for you
| KingFisher Duo Prime | KingFisher Flex | KingFisher Presto | |
|---|---|---|---|
|
|
|
|
| Size | Compact Benchtop | Benchtop | Integrate with liquid handler handler |
| Throughput | Low–Med throughput 6/12/24 samples per run/load |
Med–High throughput 24/96 samples per run |
High throughput 96 samples per run |
| Volume range | 30-5000 µl | 20-5000 µl | 50-5000 µl |
| Request demo Learn more |
Request demo Learn more |
Request demo Learn more |
|
| Compare all instruments | |||
How KingFisher technology works
The Thermo Scientific KingFisher Purification System utilizes permanent magnetic rods and disposable tip combs. When the magnetic rod—sheathed inside the tip comb—is lowered into the solution, magnetic beads collect at the bottom of the tip comb. The tip comb can then be positioned in a different row or plate, and the beads are then released by moving the magnetic rods out of the tip comb. The tip comb also facilitates the mixing of reagents with the beads by moving up and down.
Diagram details the KingFisher
workflow
Watch the video for a detail view of the workflow
Optimize your KingFisher instruments with kits & reagents, protocols, and plastics
| Nucleic Acids | Immunoprecipitation | Protein |
|---|---|---|
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| Order now Learn more |
Order now Learn more |
Order now Learn more |
| Download automated protocols | Design or customize your own protocols | |
|---|---|---|
| Nucleic Acid Protocols | IP/Protein Protocols | BindIT Software |
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|
| Search protocols | Search protocols Learn more |
Learn more |
| KingFisher Duo Prime | KingFisher Flex | KingFisher Presto |
|---|---|---|
 |
 |
 |
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|
|
| Order now | Order now | Order now |
| Nucleic Acids | Immunoprecipitation | Protein |
|---|---|---|
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|
|
| Order now Learn more |
Order now Learn more |
Order now Learn more |
| Download automated protocols | Design or customize your own protocols | |
|---|---|---|
| Nucleic Acid Protocols | IP/Protein Protocols | BindIT Software |
|
|
|
| Search protocols | Search protocols Learn more |
Learn more |
| KingFisher Duo Prime | KingFisher Flex | KingFisher Presto |
|---|---|---|
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| Order now | Order now | Order now |
KingFisher Videos
Automated Immunoprecipitation in 40 min using Dynabeads and KingFisher Flex
For IP, KingFisher instruments with Dynabeads offer the best balance of high yield and reproducibility with low nonspecific binding and cost, which is one reason why they have become the gold standard for immunoprecipitation using magnetic beads.
KingFisher Duo Prime
KingFisher Presto Sample Purification System
Resources
Brochure
Application Notes
Technical Notes
Smart Note
For Research Use Only. Not for use in diagnostic procedures.