Chromatin immunoprecipitation (ChIP) experiments examine histone modifications and genomic DNA sequences bound to specific regulatory proteins. In ChIP, protein-DNA complexes are crosslinked in vivo, immunoprecipitated, purified, and amplified for gene- and promoter-specific analysis of known targets or for the identification of new target sequences. In a related microarray-based method, ChIP-on-Chip, the immunoprecipitated DNA is labeled and hybridized to high-resolution microarrays.

Chromatin Immunoprecipitation

We offer a variety of products for chromatin immunoprecipitation, including protein A and G reagents, antibodies, and PCR and qPCR reagents.

 
 

ChIP-on-Chip

We offer a number of products for the ChIP-on-Chip workflow, including reagents for immunoprecipitation, PCR, and microarray labeling and hybridization.

 

Chromatin-Related Products

Reagents for detection of chromatin, histones, and methyltransferases, as well as DNA fragmentation and chromatin condensation.

Epigenetics Learning Center

Our Learning Center provides an overview of epigenetic regulation of gene expression as well as considerations underpinning the research workflow. Learn about:

microRNAs

DNA methylation