GeneArt CRISPR Search and Design Tool

Instant access to over 600,000 pre-design CRISPR gRNAs

Search our database of >600,000 predesigned CRISPR guide RNAs (gRNAs) targeting human and mouse genes or analyze your sequence of interest for de novo gRNA designs using our proprietary algorithms. We provide up to 25 gRNA sequences per gene with recommendations based on potential off-target effects for each CRISPR sequence. Once you’ve selected the optimal gRNA designs, purchase your gRNAs and other recommended products for genome editing directly from the Web tool.

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Hands-on CRISPR training

Before getting started, ensure the following:

1).  Is your browser supported? Thermo Fisher Cloud includes the latest data security and display features that require the use of one of the following browsers/versions:

Click on a link above to download and install a compatible browser, and thank you for using Thermo Fisher Cloud.

2). Once you are in a supported browser, you will need to log in one time only to the Thermo Fisher Cloud using your existing username and password. After your first visit to the CRISPR Search and Design tool, you will no longer be required to log in to the Cloud. 

  • You will be asked to verify your email address the first time you log in.
  • A verification request email will be sent to the email address on file for your online account. 
  • Check your spam folder if you don’t immediately receive this verification request. 
  • Future visits to the GeneArt CRISPR Search and Design Tool will not require Thermo Fisher Cloud login. 
  • Be sure to bookmark the page for future reference.


  • Learning Center
    Access genome editing application resources for more success as you plan and execute your experiments.
  • CRISPR Validated Protocols
    Getting started with CRISPR? Need proven CRISPR validated protocols? Check out our collection of step-by-step validated protocols.
  • FAQs
    Find answers to everyday problems, we have consolidated a list of most commonly asked questions.
  • Webinar Series
    Master the art of CRISPR editing by tuning into our on-demand 3 part webinar series.
  • CRISPR Hands-on Workshop
    Our experienced team has designed a comprehensive four-day workshop to get you up to speed on CRISPR.