Specifications for the Ion Proton™ Sequencer
Working environment (for indoor use only) Temperature: 68-77° F (20-25° C)
Humidity: 40-60%, noncondensing
Altitude: <6,500 ft (2,000 m)
12 in (30.5 cm) in rear
4 in (10 cm) on left side
4 in (10cm) on right side
4 in (10 cm) from front edge of bench to sequencer bezel
36 in (90 cm) aisle in front of bench for operator access
Optional rack mounting with two Ion Proton™ Sequencers per rack
Gas Supply Connection: 0.25 in push-to-connect fitting
Pressure: 30 psi
Composition: nitrogen (grade 4.8, 99.998% or better)
Other connections Ethernet: 1 GigE
USB: 2x USB 2.0
Power Voltage: 100 V (min) to 240 V (max)
Current: 14 A (max)
Frequencing: 50/60 Hz
Power Draw: 1,350 W
Dimensions Width: 21.3 in/54.2 cm
Depth: 30.5 in/77.5 cm
Height: 18.7in/47.4 cm
Weight Crated for shipment: 200 lb/90.7 kg
Free-standing: 130 lb/59 kg
Instrument compute hardware Processor: Dual 8-core Intel® Xeon® Sandy Bridge
Memory: 128 GB RAM
FPGA: Dual Altera® Stratix® V
GPU processor: 1 x NVIDIA® Tesla® C2075
Storage: 11 TB (SSD and HDD)
Operating system: Ubuntu® 11:10
Specifications for the Proton™ Torrent Server*
Product configuration A single free standing tower computer appliance, included with the purchase of the Ion Proton™ System. Includes Torrent Suite Software with all necessary software components to deliver signal processing, base calling, read alignment, and variant calling.
Processor Dual 8-core 2.9 GHz CPUs
Memory 128 GB RAM
GPU processor 2x NVIDIA® Tesla® GPUs
Storage (approx.) 27 TB (sufficient for storage of >50 Ion PI™ Chip runs)
Operating system Ubuntu 10.04
Dimensions (approx.) Width: 8.5 in/21.8 cm
Depth: 28 in/71.4 cm
Height: 17 in/43 cm
Weight (approx.) 120 lb/55 kg
Power Voltage: 100 V (min) to 240 V (max)
Frequency: 50/60 Hz
Current: 12 A (max)
Power Draw: 1,100 W


Ion Proton™ System performance specifications with Ion PI™ Chip
Throughput Up to 10 Gb
Read length Up to 200-base fragment reads
Number of reads passing filter 60-80 million reads passing filter
Sequencing run time 2-4 hours
Key applications Human-scale genome sequencing ChIP sequencing

Whole transcriptome sequencingExome sequencing
Methylation analysisGene expression by sequencing
Small genome sequencingDe novo sequencing
Small RNA sequencingGene sequencing
Areas of interest Agricultural research Stem cell research
Cancer research Epigenomics Ancient DNA genomics
Forensic scienceMetagenomics
Barcoding solutions 384 barcodes supported by Torrent Suite Software
96 off-the-shelf barcodes for DNA
16 off-the-shelf barcodes for RNA
Software solutions

Torrent Suite Software utilizing Torrent Browser including TMAP alignment and Torrent Variant Caller for germline or somatic mutation detection.

Torrent Browser (included) offers users remote web access to instrument status monitoring, run quality reports, individual data files, and extensible plug-ins for application-specific analysis.

Plugins available for download from the Torrent Browser Plugin Store for analysis of genome sequencing, targeted sequencing, variant analysis and annotation, microbial sequencing, transfer to 3rd party bioinformatics packages, and more.

Data can optionally flow into Ion Reporter™ Software for controlled analysis, annotation, and reporting of variants. Ion Reporter™ Software provides application specific workflows to support single, trio and paired tumor normal analysis

Data formats Industry standard FASTQ, SFF, BAM and VCF format outputs

†Space-saving rack can be purchased for the Ion Proton™ System. Contact your sales representative for details.

The trademarks mentioned herein are the property of Thermo Fisher Scientific Inc. and/or its affiliate(s) or their respective owners. Intel and Xeon are registered trademarks of Intel Corporation. NVIDIA and Tesla are registered trademarks of NVIDIA Corporation. Altera and Stratix are registered trademarks of of Altera Corporation. Ubuntu is a registered trademark of Canonical Ltd.