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Custom chromatography resin development

Through its unique product attributes, POROS chromatography resins help maintain performance and add flexibility to your downstream process. Combine high resolution and high capacity in a custom chromatography resin tailored to your specific process requirements.

Request information  Technical resources

Resin development includes the use of Design of Experiments (DoE) to define the resin-manufacturing process required for your purification needs. DoE screening includes pore size, ligand density, and coupling chemistry to optimize performance for your biotherapeutic. Start the process with your ligand or another commercially available ligand, select from our library of existing CaptureSelect ligands, or generate a custom CaptureSelect ligand for your application.

All process validation and regulatory requirements are fully supported by an ISO 9001/13845 quality management system.


Custom POROS resin development program

Prototype resin development

  • Customer information
  • Experimental design
  • Proposal

 

Process definition

  • Process optimization
  • Scale-up

Commercialization

  • Process validation
  • Stability studies
  • Regulatory support package

 


Request a technical meeting

Unlock the power of POROS chromatography, and develop a platform purification process for any biotherapeutic.

To arrange a technical meeting with our resin development scientists; simply submit your request for more information and our local sales representative will follow-up with you to organize the meeting.

Technical resources and literature

Posters:

Poster: Enabling custom solutions for downstream processing

Poster: C-tag affinity tag, from routine protein purification to use in a cGMP production process

Scientific publications:

Pabst, TM et al. (2016) Camelid VHH affinity ligands enable separation of closely related biopharmaceuticals. Biotechnol. J. doi: 10.1002/biot.201600357

 

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Bioprocessing resources

Click below to access products brochures, training videos, mobile apps, and more.

Support

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