Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
We offer a unique service for the development of product- and/or process-specific affinity solutions tailored to a target protein and its specific requirements.
The custom ligand can be immobilized on a variety of backbones, including POROS resins, and further developed into an affinity resin, which can be used in large-scale processing of biopharmaceuticals.
Library construction 1 to 10 targets | Lead screening 200 → 24 → 6 | Prototype resin testing 6 → 2 | Lead selection 2 → 1 | cGMP suitable resin |
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Ligand screen:
| Prototype screen:
| Lead testing:
| Final resin:
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No matter what your development challenges are, we are here to help. Our experienced team of scientists and technical specialists is ready to assist you with custom application solution. Complete this form to start the conversation and move towards a custom solution designed just for you.
Through our library development process we have identified a number of candidates that may serve as excellent starting points for a custom affinity resin program. Pipeline opportunities include:
Table 1. CaptureSelect affinity products for purification
Product Stage | Therapeutic Proteins | Viruses | Antibody Types |
Research scale purification resins | Antithrombin III (ATIII) | Adenovirus (Adv5) | IgA (Fc) |
Lead Selection | Prothrombin (Factor II) | Influenza (HA) | IgG-Fc (mouse) |
Prototype resin testing | Universal affinity tag (Uni-Tag) | Baculovirus | |
Lead Screening | Interferon alpha and beta (IFNalpha/beta) | Exosomes | scFv / human VH |
Library Construction | CHO host cell proteins |
| IgG-Fc (rat) |
Posters:
Scientific publications:
Access a targeted collection of scientific application notes, case studies, posters, white papers and more for bioprocessing:
For Research Use or Further Manufacturing. Not for diagnostic use or direct administration in to humans or animals.