CaptureSelect purification products enable the efficient capture of therapeutic proteins from any feed stream, thereby helping reduce the number of process steps, increase yield, as well as provide a platform approach for purifying any target biotherapeutic.

Request information  Technical resources

We offer a unique service for the development of product- and/or process-specific affinity solutions tailored to a target protein and its specific requirements.

The custom ligand can be immobilized on a variety of backbones, including POROS resins, and further developed into an affinity resin, which can be used in large-scale processing of biopharmaceuticals.

Custom CaptureSelect resin development program

Library construction
1 to 10 targets

200 → 24 → 6

Ligand screen:

  • Specificity
  • Binding kinetics
  • Mild elution
  • Stability


resin testing
6 → 2

Prototype screen:

  • Ligand scalability
  • One-step purity with feedstock
  • Elution profiles
  • Ligand stability


2 → 1

Lead testing:

  • Larger scale production of lead prototypes
  • Resin evaluation under process conditions


suitable resin

Final resin:

  • Process validation
  • Leakage ELISA
  • Regulatory support file


Request a technical meeting

No matter what your development challenges are, we are here to help. Our experienced team of scientists and technical specialists is ready to assist you with custom application solution. Complete this form to start the conversation and move towards a custom solution designed just for you. 

Find your solution ›

Start from existing candidates in our pipeline

Through our library development process we have identified a number of candidates that may serve as excellent starting points for a custom affinity resin program. Pipeline opportunities include:

Table 1. CaptureSelect affinity products for purification

Product Stage

Therapeutic Proteins


Antibody Types

Research scale purification resins

Antithrombin III (ATIII)
Fibrinogen (Factor I)
Transferrin (TF)
Apolipoprotein H (ApoH)
C1-inhibitor (C1-Inh)
Granulocyte-macrophage colony-stimulating factor (GM-CSF)

Adenovirus (Adv5)

IgA (Fc)
Bovine IgA
Rabbit IgG (Fc)

Lead Selection

Prothrombin (Factor II)
Deoxyribonuclease (DNAse)

Influenza (HA)

IgG-Fc (mouse)

Prototype resin testing

Universal affinity tag (Uni-Tag)
Factor X



Lead Screening

Interferon alpha and beta (IFNalpha/beta)
Interleukin 2 (hIL2)
Factor V, FXI, FXII, FXIII, and FH
Erythropoietin (EPO)

Lentivirus (VSV-G)

scFv / human VH

Library Construction

CHO host cell proteins


IgG-Fc (rat)

Technical resources and literature


Scientific publications:

Bioprocessing resources

Click below to access products brochures, training videos, mobile apps, and more.


 Request more info on Bioprocessing

For Research Use or Further Manufacturing. Not for diagnostic use or direct administration in to humans or animals.