Reproducible separations time after time

Reproducible separations time after time

Thermo Scientific Vanquish and UltiMate 3000 pumps provide industry-leading flow, pressure, and precision. Choose from:

  • Binary pump for speed
  • Quaternary pumps for flexibility in solvent proportioning
  • Dual gradient pump for high throughput or 2D-LC applications
  • Isocratic pump for a cost-effective workhorse
  • Nano/capillary pumps for accurate gradients at low flow rates

Which platform should I choose?

Vanquish HPLC and UHPLC pumps allow you to experience the lowest gradient delay, exceptional gradient profiles, unmatched flow accuracy, and extreme durability. With SmartFlow technology that automatically compensates for changing eluent compressibility, these pumps deliver the precise performance and flexibility needed for your application, from routine quality control to the most demanding of research.

UltiMate 3000 HPLC and UHPLC Pumps deliver proven dependability, meeting the needs and requirements of your application with an extensive range of options.


Learn more about HPLC and UHPLC pumps

Choose these pumps for throughput, high-resolution HPLC, UHPLC, or LC-MS applications. Use the biocompatible semi-preparative binary pump to purify μg to low mg biological compounds.

Obtain consistent results from smooth flow delivery and exceptional gradient precision with the Thermo Scientific Vanquish Binary Pump H. The parallel dual independent piston mechanism with variable stroke volume allows you to enjoy the lowest pulsation possible, even at 150 MPa. Use these extended pressures for high-resolution and high-throughput applications with ease: the entire system, including proprietary injection and switching valves, is built for it.

Alternatively, the Thermo Scientific Vanquish Binary Pump F and Vanquish Binary Pump C deliver excellent flow consistency through intelligent adjustments of the cam shaft speed during compression. This results in unrivaled retention time precision and the highest data confidence for your routine, high throughput analyses.

  Binary Pump H Binary Pump F Binary Pump C
Pressure Range
2-151 MPa

2-103 MPa

2-70 MPa
Settable Flow Range
0.001–5 mL/min, in 1 μL/min increments

0.001–8 mL/min, in 1 μL/min increments

0.001–10 mL/min, in 1 μL/min increments
Pulsation
<0.4%

<1.0%

<1.0%
Mixer Volume
25 µL

200 µL

200 µL
Solvent Degassing
Biocompatible
HPG-3200SD Standard Binary Pump Delivering accurate gradients and precise retention times at pressures up to 62 MPa and flow rates up to 10 mL/min.
HPG-3400SD Standard Binary Pump Increase your binary method flexibility by combining four different mobile phases, two at a time, at pressures up to 62 MPa and flow rates up to 10 mL/min.
HPG-3200RS Rapid Separation Binary Pump Providing more performance in ultra-high speed and ultra-high resolution applications at pressures up to 100 MPa and flow rates up to 8 mL/min.
HPG-3400RS Rapid Separation Binary Pump Get more performance and mobile phase flexibility in ultra-high speed and ultra-high resolution applications by combining four different mobile phases, two at a time, at pressures up to 100 MPa and flow rates up to 8 mL/min.
HPG-3200BX Biocompatible Binary Semi-Preparative Pump Purify biological compounds in the microgram to lower-milligram range quickly and accurately at pressures up to 16.5 MPa and flow rates up to 50 mL/min (or 100 mL/min for isocratic applications).

Obtain consistent results from smooth flow delivery and exceptional gradient precision with the Thermo Scientific Vanquish Binary Pump H. The parallel dual independent piston mechanism with variable stroke volume allows you to enjoy the lowest pulsation possible, even at 150 MPa. Use these extended pressures for high-resolution and high-throughput applications with ease: the entire system, including proprietary injection and switching valves, is built for it.

Alternatively, the Thermo Scientific Vanquish Binary Pump F and Vanquish Binary Pump C deliver excellent flow consistency through intelligent adjustments of the cam shaft speed during compression. This results in unrivaled retention time precision and the highest data confidence for your routine, high throughput analyses.

  Binary Pump H Binary Pump F Binary Pump C
Pressure Range
2-151 MPa

2-103 MPa

2-70 MPa
Settable Flow Range
0.001–5 mL/min, in 1 μL/min increments

0.001–8 mL/min, in 1 μL/min increments

0.001–10 mL/min, in 1 μL/min increments
Pulsation
<0.4%

<1.0%

<1.0%
Mixer Volume
25 µL

200 µL

200 µL
Solvent Degassing
Biocompatible
HPG-3200SD Standard Binary Pump Delivering accurate gradients and precise retention times at pressures up to 62 MPa and flow rates up to 10 mL/min.
HPG-3400SD Standard Binary Pump Increase your binary method flexibility by combining four different mobile phases, two at a time, at pressures up to 62 MPa and flow rates up to 10 mL/min.
HPG-3200RS Rapid Separation Binary Pump Providing more performance in ultra-high speed and ultra-high resolution applications at pressures up to 100 MPa and flow rates up to 8 mL/min.
HPG-3400RS Rapid Separation Binary Pump Get more performance and mobile phase flexibility in ultra-high speed and ultra-high resolution applications by combining four different mobile phases, two at a time, at pressures up to 100 MPa and flow rates up to 8 mL/min.
HPG-3200BX Biocompatible Binary Semi-Preparative Pump Purify biological compounds in the microgram to lower-milligram range quickly and accurately at pressures up to 16.5 MPa and flow rates up to 50 mL/min (or 100 mL/min for isocratic applications).

Choose these pumps for the widest possible application range with maximum flexibility in mobile phase composition and stable retention times.

  Quaternary Pump F Quaternary Pump C/CN
Pressure Range
2-103 MPa

2-70 MPa
Settable Flow Range
0.001–8 mL/min, in 1 μL/min increments

0.001–10 mL/min, in 1 μL/min increments
Integrated Solvent Degassing
Biocompatible
LPG-3400SD Standard Quaternary Pump Delivering flexibility by combining up to four different mobile phases at pressures up to 62 MPa and flow rates up to 10 mL/min.
LPG-3400RS Rapid Separation Quaternary Pump Increase your performance without sacrificing flexibility by combining up to four different mobile phases at pressures up to 100 MPa and flow rates up to 8 mL/min.
LPG-3400XRS Extended Pressure Range Quaternary Pump Enjoy the flexibility of a quaternary pump with the fast gradient performance of a binary pump. Combining up to four different mobile phases with a minimized gradient delay volume at pressures up to 125 MPa.
  Quaternary Pump F Quaternary Pump C/CN
Pressure Range
2-103 MPa

2-70 MPa
Settable Flow Range
0.001–8 mL/min, in 1 μL/min increments

0.001–10 mL/min, in 1 μL/min increments
Integrated Solvent Degassing
Biocompatible
LPG-3400SD Standard Quaternary Pump Delivering flexibility by combining up to four different mobile phases at pressures up to 62 MPa and flow rates up to 10 mL/min.
LPG-3400RS Rapid Separation Quaternary Pump Increase your performance without sacrificing flexibility by combining up to four different mobile phases at pressures up to 100 MPa and flow rates up to 8 mL/min.
LPG-3400XRS Extended Pressure Range Quaternary Pump Enjoy the flexibility of a quaternary pump with the fast gradient performance of a binary pump. Combining up to four different mobile phases with a minimized gradient delay volume at pressures up to 125 MPa.

Choose these pumps for increased sample throughput, higher productivity, or switching between applications without re-plumbing. Dual pumps have two built-in ternary pumps for the highest flexibility and optimal use of lab space.

  Dual Pump F Dual Pump C/CN
Settable Flow Range
0.001–8 mL/min, in 1 μL/min increments

0.001–10 mL/min, in 1 μL/min increments
Pressure Range
2 – 103 MPa

2-70 MPa
Integrated Solvent Degassing
Biocompatible
DGP-3600SD Dual-Gradient Standard Pump Increase sample throughput, achieve higher chromatographic resolution, or automate sample preparation.
DGP-3600RS Dual-Gradient Rapid Separation Pump Increase sample throughput, achieve higher chromatographic resolution, or automate sample preparation for ultra-high speed and ultra-high resolution applications.
  Dual Pump F Dual Pump C/CN
Settable Flow Range
0.001–8 mL/min, in 1 μL/min increments

0.001–10 mL/min, in 1 μL/min increments
Pressure Range
2 – 103 MPa

2-70 MPa
Integrated Solvent Degassing
Biocompatible
DGP-3600SD Dual-Gradient Standard Pump Increase sample throughput, achieve higher chromatographic resolution, or automate sample preparation.
DGP-3600RS Dual-Gradient Rapid Separation Pump Increase sample throughput, achieve higher chromatographic resolution, or automate sample preparation for ultra-high speed and ultra-high resolution applications.

Gain access to the Thermo Scientific Vanquish Liquid Chromatography platform with the Thermo Scientific Vanquish Isocratic Pump C. Providing SmartFlow pumping technology on a single solvent line, excellent flow and retention time precision can be obtained for isocratic separations at backpressures up to 70 MPa.

ISO-3100SD Standard Isocratic Pump Enjoy cost effective, robust and dependable isocratic performance. Suitable for QA/QC and refractive index detection or as an auxiliary HPLC pump.
ISO-3100BM Biocompatible Isocratic Pump Ensure optimal sensitivity for low level analytes in small samples using electrochemical (EC) detection.

Gain access to the Thermo Scientific Vanquish Liquid Chromatography platform with the Thermo Scientific Vanquish Isocratic Pump C. Providing SmartFlow pumping technology on a single solvent line, excellent flow and retention time precision can be obtained for isocratic separations at backpressures up to 70 MPa.

ISO-3100SD Standard Isocratic Pump Enjoy cost effective, robust and dependable isocratic performance. Suitable for QA/QC and refractive index detection or as an auxiliary HPLC pump.
ISO-3100BM Biocompatible Isocratic Pump Ensure optimal sensitivity for low level analytes in small samples using electrochemical (EC) detection.

Obtain accurate gradients at the lowest nano flow rates to maximize sensitivity. Switch between nano, capillary, and micro flow rates without tools in minutes.

The UltiMate NCS-3500RS Binary Rapid Separation Nano/Capillary Pumps offer flexibility for 2D applications and have a heated column compartment for improved precision.

Need quality HPLC pump parts?
Need quality HPLC pump parts?

Get reliable performance and productivity with quality parts and accessories designed for your HPLC/UHPLC pump.

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