Which HPLC and UHPLC pump is right for you?

Experience industry-leading flow, pressure and precision when you use Thermo Scientific Vanquish pumps. We offer binary pumps for speed, quaternary pumps for flexibility in solvent proportioning, dual gradient pumps for high throughput and 2D-LC applications, cost-effective and robust isocratic pumps and nano/capillary/micro pumps for accurate gradients at low flow rates. Vanquish HPLC and UHPLC pumps provide the lowest gradient delay, exceptional gradient profiles, unmatched flow accuracy, and extreme durability with built-in Thermo Scientific SmartFlow technology to automatically compensate for changing eluent compressibility and deliver precise performance and flexibility.

Discover HPLC and UHPLC Pumps

HPLC and UHPLC pump categories














High throughput for high-resolution HPLC, UHPLC or LC-MS applications. Wide application range and flexibility in mobile phase composition. Increased productivity, flexibility and switching between applications without re-plumbing. Stable peak retention times for routine isocratic applications.

Build your ideal HPLC or UHPLC with our step-by-step configurator

Binary pumps

Choose binary pumps for throughput, high-resolution HPLC, UHPLC or LC-MS applications. Use the biocompatible semi-preparative binary pump to purify µg to low-mg biological compounds.

Vanquish binary pumps

Supplying flow consistency and gradient precision for unrivaled retention time and confidence in data, Vanquish binary pumps are built to make the most of extended pressure for high-throughput, high-resolution applications. All Vanquish pumps use SmartFlow technology to automatically compensate for changing eluent compressibility and biocompatible versions are available. 

Quaternary pumps

Thermo Scientific quaternary pumps offer the widest possible application range with maximum flexibility in mobile phase composition and stable retention times.

Vanquish quaternary pumps

Ensuring excellent flow and gradient precision through SmartFlow technology, Thermo Scientific Vanquish quaternary pumps offer unrivaled retention time precision and confidence in your data, even when running ternary and quaternary gradients. They also provide more freedom for method transfer, method development, and application switching.

Dual-gradient pumps

Thermo Scientific dual-gradient HPLC and UHPLC pumps offer increased sample throughput, higher productivity, or switching between applications without re-plumbing. Dual pumps have two built-in ternary pumps for the highest flexibility and optimal use of lab space.

Vanquish dual pumps

Using two independent ternary-solvent flow streams in a single housing, Thermo Scientific Vanquish dual pumps deliver application flexibility for dual LC, tandem LC or LC-MS, and inverse gradient workflows. These pumps use SmartFlow technology to automatically compensate for changing eluent compressibility and ensure excellent flow and gradient precision, independent of eluent composition.

Isocratic Pumps

Thermo Scientific isocratic pumps provide stable peak retention times for routine isocratic applications. These pumps are ideal for: QA/QC using refractive index detection; high sensitivity for low-level analytes when used with an electrochemical pump; or as an auxiliary pump for LC-MS make-up flows.

Vanquish isocratic pumps

Featuring SmartFlow pumping technology on a single solvent line, Thermo Scientific Vanquish isocratic pumps offer excellent flow and retention time precision for isocratic separations at backpressures up to 700 bar.

Nano/Capillary/Micro pumps

Obtain accurate gradients at the lowest nano flow rates to maximize sensitivity.

Vanquish Neo UHPLC system

For researchers pursuing the next scientific breakthrough, the Thermo Scientific Vanquish Neo UHPLC system delivers maximum performance 24/7 for nano-, capillary-, and micro-flow LC-MS. Thermo Scientific ProFlow XR 1500 bar pump technology ensures excellent retention time precision from nano-flow up to 100 µL/min. Pump is available as part of the Vanquish Neo system.

HPLC standards, reagents & solvents

Control retention time and selectivity, resolve complex ionic mixtures without using ion exchange columns and improve peak symmetry for your chromatography analyses by using the right reagents.

Contact us to get a quote or discuss an HPLC/UHPLC solution