Confident quantitation with triple quadrupole LC-MS systems
From addressing complexities of molecules and matrices, to ensuring ease-of-use while satisfying regulatory requirements—today’s challenges in targeted quantitation involve more than just measuring concentrations of target analytes. Achieve ultimate confidence in your data quality with a robust, sensitive, reproducible, and reliable targeted quantitation method using our new liquid chromatography mass spectrometry (LC/MS) workflow solutions. Our TSQ Triple Quadrupole MS systems also come with a Three Year Factory Warranty so you can gain peace of mind.
Triple quadrupole LC-MS system product comparison
Different applications require different levels of system sensitivity, resolution, and speed. In this table, we compare different TSQ triple quadrupole systems in order to showcase which ones are most relevant to your laboratory's needs. For more information on these systems, click on our Smartnote: Transitioning to Confident Quantitation – in search of a better tomorrow
|Triple Quad Product Comparison||Fortis||Quantis|
|Applications across multiple matrices|
|Targeted quantitation in Proteomics||No||Yes||Yes|
|Peptide and protein quantitation (Biopharma)||No||Yes||Yes|
|Small molecule quantitation (Pharma, Clinical Research)||Yes||Yes||Yes|
|Small molecule mixture quantitation (Environmental Safety, Food Safety, Forensic Toxicology, Pharma)||Yes||Yes||Yes|
|Analysis and targeted quantitation of trace impurities (Impurity Quantitation)||Yes||Yes||Yes|
|Targeted quantitation in Omics (metabolomics, lipidomics)||Yes||Yes||Yes|
|SRM for reliable identification||Yes||Yes||Yes|
|Multiple Source Compatibility||Yes||Yes||Yes|
|High Resolution SRM: for increased selectivity and sensitivity for analytes or multiple analytes in complex matrices||++||++||+++|
|Segmented quadrupoles for increased ion efficiency||Yes||Yes||Yes|
|Neutral blocker for increased robustness||Yes||Yes||Yes|
|Increased dynodes in detector for increased lifetime and better linear dynamic range||Yes||Yes||Yes|
|APCI compatible with HESI source||Yes||Yes||Yes|
|Polarity Switching: Fast switching with stabilization enable faster quantitation assays for every molecule type||Yes||Yes||Yes|
|System Remote Monitoring||Yes||Yes||Yes|
|Instrument IQ/OQ assist||Yes||Yes||Yes|
|Thermo Fisher Cloud: Access, process, review data whenever you like, from wherever you are||No||Yes||Yes|
|Wi-Fi Connectivity: Access your data, Check your assay performance remotely||Yes||Yes||Yes|
|Size||27x30x33 (in)||27x30x33 (in)||27x30x33 (in)|
|Compatible separation technologies||UltiMate, Vanquish, Multiplexing, Capillary LC, Other vendors||UltiMate, Vanquish, Other vendors, IC, Multiplexing, Capillary LC, NanoLC||UltiMate, Vanquish, Other vendors, IC, Multiplexing, Capillary LC, NanoLC|
|Compatible Software?||Xcalibur, TraceFinder, Chromeleon||Xcalibur, TraceFinder, Chromeleon||Xcalibur, TraceFinder, Chromeleon|
Common applications of triple quadrupole technology
To perform quantitation assays with confidence, you need a liquid chromatography mass spectrometry (LCMS) workflow solution that is relevant to your laboratory’s goals. These workflow solutions are adapted to specific applications, including clinical research, environmental and food safety, forensic toxicology, and pharma/biopharma.
Maximize your return on investment in a unified Thermo Scientific mass spectrometry architecture from data acquisition and analysis solutions
Promotions and featured content
Greater proteome coverage and sensitivity
The Thermo Scientific FAIMS Pro Duo interface enhances precursor selectivity, improving qualitative and quantitative results for most peptide and protein applications while reducing time-consuming sample preparation steps. The FAIMS Pro Duo interface increases analytical performance through gas-phase fractionation and selective enhancement of peptidic compounds, reducing the complexity of MS spectra, and improving the analyte signal-to-noise ratio. The end result is greater proteome coverage, enhanced sensitivity and more accurate quantitation.
Expand your application knowledge
Our LC-MS on-demand webinar series expands your application knowledge for pharma, biopharma, environmental, omics, food, forensics and clinical research and more. Learn how the latest high-performance mass spectrometry solutions can enable your laboratory to solve your most pressing analytical challenges, regardless of sample type.
Lab ideas for people – like yourself– in analytical labs making medicines, directed by topics, ideas and thoughts from your fellow medicine makers. Each month, a new theme addresses challenges and solutions around technology and workflows.