NanoDrop Products Guide

Pipette. Measure. Know.

Quantify DNA, RNA and protein samples in seconds with only 1–2 µL using Thermo Scientific NanoDrop instruments. Whether you choose a NanoDrop UV-Vis spectrophotometer or fluorospectrometer, you can rely on patented* NanoDrop technology for accurate, fast results to assess sample concentration and purity. 

UV-Vis solutions in Biopharma and Biosciences
UV-Vis solutions in Biopharma and Biosciences

Hear about the latest applications and advancements for UV-Vis spectrophotometry in biopharma and biosciences research. Register to access all 5 sessions.

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Choose the NanoDrop instrument that's right for you

Simplify DNA, RNA, and protein quantitation with direct sample measurement.

 NanoDrop One/Oneᶜ
NanoDrop Eight
NanoDrop Lite Plus
NanoDrop 3300
Full-spectrum microvolume UV-Vis measurements with a cuvette option in a single instrument

Higher throughput, full-spectrum microvolume UV-Vis measurements

Basic microvolume UV measurements

Full-spectrum microvolume fluorescence measurements
Measures 1-2 μL sample

Dynamic range (ng/μL dsDNA)2.027,500*
ng/μL for dsDNA
2.0 - 10,000
ng/μL for dsDNA
ng/μL for dsDNA
< 1 fmol
Full-spectral data


Pre-programmed methods for nucleic acids and proteins

Measures nucleic acid A260/A280 ratio

Measures nucleic acid A260/A230 ratio

Measures purified protein A280

Measures protein A260/A280 ratio

Pre-programmed methods for colorimetric assays (BCA, Bradford, Lowry, Pierce 660)

Measures protein and peptides at A205

Custom methods


Built-in cuvette option

Standalone local control



High-resolution touchscreen interface


Measures fluorescently-labeled nucleic acid and protein samples using absorbance

Coming soon

Measures a wide variety of fluorescence assays: RiboGreen™, PicoGreen™, GFP, BFP mutants, Hoechst, 4-MU, Quantum Dots, OPA, DyLite™, Alexa Fluor™, etc.   

Measures multiple fluorophores from a single sample   

Autoblank & Automeasure

Contaminant identification

21 CFR Part 11 regulatory complianceWith Optional SoftwareWith Optional Software  
Embedded technical support

Password protected accessOptional Security Suite Software

Optional SciVault Software


Enhanced connectivity (Wi-Fi and Bluetooth™)

Thermo Fisher Connect (Cloud enabled)


* lowest detection limit is 0.2 ng/μL with 10 mm cuvette

Move one step closer with next-generation microvolume UV-Vis

Be more successful in downstream applications when you qualify your sample before use with the NanoDrop One UV-Vis spectrophotometer built with novel Thermo Scientific Acclaro Sample Intelligence Technology.


NanoDrop Free Trial Program

Test a NanoDrop instrument in your laboratory with your own samples and convince yourself.

For research use only. Not for diagnostic purposes. Bluetooth is a registered trademark of Bluetooth SIG, Inc. All other trademarks are the property of Thermo Fisher Scientific and its subsidiaries. All NanoDrop instruments are approved to CE and UL/CSA.

* Patents US6628382 and US6809826.