Pipette. Measure. Know.
Quantify DNA, RNA and protein samples in seconds with only 1–2 µL using Thermo Scientific NanoDrop instruments. Whether you choose a NanoDrop UV-Vis spectrophotometer or fluorospectrometer, you can rely on patented* NanoDrop technology for accurate, fast results to assess sample concentration and purity.
Hear about the latest applications and advancements for UV-Vis spectrophotometry in biopharma and biosciences research. Register to access all 5 sessions.
Choose the NanoDrop instrument that's right for you
Simplify DNA, RNA, and protein quantitation with direct sample measurement.
| NanoDrop One/Oneᶜ UV-Vis | NanoDrop Eight UV-Vis | NanoDrop Lite Plus UV | NanoDrop 3300 Fluorescence | |
 Full-spectrum microvolume UV-Vis measurements with a cuvette option in a single instrument |  Higher throughput, full-spectrum microvolume UV-Vis measurements |  Basic microvolume UV measurements |  Full-spectrum microvolume fluorescence measurements | |
| Measures 1-2 μL sample | ✓ | ✓ | ✓ | ✓ |
| Dynamic range (ng/μL dsDNA) | 2.0–27,500* ng/μL for dsDNA | 2.0 - 10,000 ng/μL for dsDNA | 2–1,500 ng/μL for dsDNA | < 1 fmol (FITC) |
| Full-spectral data | ✓ | ✓ | ✓ | |
| Pre-programmed methods for nucleic acids and proteins | ✓ | ✓ | ✓ | ✓ |
| Measures nucleic acid A260/A280 ratio | ✓ | ✓ | ✓ | |
| Measures nucleic acid A260/A230 ratio | ✓ | ✓ | ✓ | |
| Measures purified protein A280 | ✓ | ✓ | ✓ | |
| Measures protein A260/A280 ratio | ✓ | ✓ | ✓ | |
| Pre-programmed methods for colorimetric assays (BCA, Bradford, Lowry, Pierce 660) | ✓ | ✓ | ||
| Measures protein and peptides at A205 | ✓ | ✓ | ||
| Custom methods | ✓ | ✓ | ✓ | |
| Built-in cuvette option | ✓ | |||
| Standalone local control | ✓ | ✓ | ||
High-resolution touchscreen interface | ✓ | ✓ | ||
| Measures fluorescently-labeled nucleic acid and protein samples using absorbance | ✓ | Coming soon | ✓ | |
| Measures a wide variety of fluorescence assays: RiboGreen™, PicoGreen™, GFP, BFP mutants, Hoechst, 4-MU, Quantum Dots, OPA, DyLite™, Alexa Fluor™, etc. | ✓ | |||
| Measures multiple fluorophores from a single sample | ✓ | |||
| Autoblank & Automeasure | ✓ | ✓ | ||
| Contaminant identification | ✓ | ✓ | ||
| 21 CFR Part 11 regulatory compliance | With Optional Software | With Optional Software | ||
| Embedded technical support | ✓ | ✓ | ||
| Password protected access | Optional Security Suite Software | Optional SciVault Software | ✓ | |
| Enhanced connectivity (Wi-Fi and Bluetooth™) | ✓ | |||
| Thermo Fisher Connect (Cloud enabled) | ✓ |
* lowest detection limit is 0.2 ng/μL with 10 mm cuvette
Move one step closer with next-generation microvolume UV-Vis
Be more successful in downstream applications when you qualify your sample before use with the NanoDrop One UV-Vis spectrophotometer built with novel Thermo Scientific Acclaro Sample Intelligence Technology.
NanoDrop Free Trial Program
Test a NanoDrop instrument in your laboratory with your own samples and convince yourself.
For research use only. Not for diagnostic purposes. Bluetooth is a registered trademark of Bluetooth SIG, Inc. All other trademarks are the property of Thermo Fisher Scientific and its subsidiaries. All NanoDrop instruments are approved to CE and UL/CSA.
* Patents US6628382 and US6809826.
